inst/www/helpfiles/filter_correlation_distrib.md

In ChromSCape: Analysis of single-cell epigenomics datasets with a Shiny App

Filter lowly correlated cells

To improve the stability of the clustering and to remove from the analysis isolated cells that do not belong to any subgroup, cells displaying a Pearson’s pairwise correlation score below a threshold t with at least p % of cells are filtered (p is set at 1 % by default). The correlation threshold t is calculated as a percentile of Pearson’s pairwise correlation scores for a randomized dataset (percentile is recommended to be set as the 99th percentile). The correlation threshold is represented by the red line on the distribution plot.

ChromSCape documentation built on Nov. 8, 2020, 6:57 p.m.