Description Format Details Value
Biomarkers that predict disease progression might assist the development of better therapeutic strategies for aggressive cancers, such as ovarian cancer. Here, we investigated the role of collagen type XI alpha 1 (COL11A1) in cell invasiveness and tumor formation and the prognostic impact of COL11A1 expression in ovarian cancer. Microarray analysis suggested that COL11A1 is a disease progression-associated gene that is linked to ovarian cancer recurrence and poor survival. Small interference RNA-mediated specific reduction in COL11A1 protein levels suppressed the invasive ability and oncogenic potential of ovarian cancer cells and decreased tumor formation and lung colonization in mouse xenografts. A combination of experimental approaches, including real-time RT-PCR, casein zymography and chromatin immunoprecipitation (ChIP) assays, showed that COL11A1 knockdown attenuated MMP3 expression and suppressed binding of Ets-1 to its putative MMP3 promoter-binding site, suggesting that the Ets-1-MMP3 axis is upregulated by COL11A1. Transforming growth factor (TGF)-beta (TGF-??1) treatment triggers the activation of smad2 signaling cascades, leading to activation of COL11A1 and MMP3. Pharmacological inhibition of MMP3 abrogated the TGF-??1-triggered, COL11A1-dependent cell invasiveness. Furthermore, the NF-YA-binding site on the COL11A1 promoter was identified as the major determinant of TGF-??1-dependent COL11A1 activation. Analysis of 88 ovarian cancer patients indicated that high COL11A1 mRNA levels are associated with advanced disease stage. The 5-year recurrence-free and overall survival rates were significantly lower (P=0.006 and P=0.018, respectively) among patients with high expression levels of tissue COL11A1 mRNA compared with those with low expression. We conclude that COL11A1 may promote tumor aggressiveness via the TGF-??1-MMP3 axis and that COL11A1 expression can predict clinical outcome in ovarian cancer patients.
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 | experimentData(eset):
Experiment data
Experimenter name: Wu Y, Chang T, Huang Y, Huang H, Chou C
Laboratory: Wu, Chou 2013
Contact information:
Title: COL11A1 promotes tumor progression and predicts poor clinical outcome in ovarian cancer.
URL:
PMIDs: 23934190
Abstract: A 260 word abstract is available. Use 'abstract' method.
Information is available on: preprocessing
notes:
platform_title:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
platform_shorttitle:
Affymetrix HG-U133Plus2
platform_summary:
hgu133plus2
platform_manufacturer:
Affymetrix
platform_distribution:
commercial
platform_accession:
GPL570
platform_technology:
in situ oligonucleotide
version:
2015-09-22 20:02:05
featureData(eset):
An object of class 'AnnotatedDataFrame'
featureNames: 1007_s_at 1053_at ... AFFX-HUMISGF3A/M97935_MB_at
(42447 total)
varLabels: probeset gene EntrezGene.ID best_probe
varMetadata: labelDescription
|
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 | assayData: 42447 features, 60 samples
Platform type:
---------------------------
Available sample meta-data:
---------------------------
alt_sample_name:
Tc_113 Tc_48 Tc_49 Tc_51 Tc_56 Tc_59 Tc_61 Tc_63 Tc_64 Tc_65 Tc_74
1 1 1 1 1 1 1 1 1 1 1
Tc_94 Te_69 Te_77 Te_78 Te_79 Te_84 Te_87 Te_89 Te_90 Te_91 Te_92
1 1 1 1 1 1 1 1 1 1 1
Te_93 Tm_101 Tm_102 Tm_106 Tm_107 Tm_110 Tm_95 Tm_96 Tm_97 Tm_98 Ts_11
1 1 1 1 1 1 1 1 1 1 1
Ts_14 Ts_15 Ts_17 Ts_19 Ts_2 Ts_20 Ts_21 Ts_23 Ts_24 Ts_26 Ts_28
1 1 1 1 1 1 1 1 1 1 1
Ts_3 Ts_31 Ts_32 Ts_34 Ts_35 Ts_36 Ts_37 Ts_39 Ts_4 Ts_41 Ts_43
1 1 1 1 1 1 1 1 1 1 1
Ts_45 Ts_46 Ts_47 Ts_5 Ts_8
1 1 1 1 1
sample_type:
tumor
60
histological_type:
clearcell endo mucinous ser
12 11 9 28
summarystage:
early late
25 35
tumorstage:
1 2 3 4
17 8 30 5
recurrence_status:
norecurrence recurrence
40 20
os_binary:
long short
44 16
relapse_binary:
long short
40 20
batch:
2010-09-07 2010-09-08 2010-10-14 2010-12-10 2010-12-14
20 2 18 16 4
uncurated_author_metadata:
title: Tc_113///geo_accession: GSM1078972///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: clear cell///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tc_48///geo_accession: GSM1078973///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: clear cell///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: death///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tc_49///geo_accession: GSM1078974///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: clear cell///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tc_51///geo_accession: GSM1078975///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: clear cell///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tc_56///geo_accession: GSM1078976///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: clear cell///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tc_59///geo_accession: GSM1078977///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: clear cell///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tc_61///geo_accession: GSM1078978///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: clear cell///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tc_63///geo_accession: GSM1078979///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: clear cell///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tc_64///geo_accession: GSM1078980///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: clear cell///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tc_65///geo_accession: GSM1078981///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: clear cell///characteristics_ch1.2: advanced disease stage: stage II///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tc_74///geo_accession: GSM1078982///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: clear cell///characteristics_ch1.2: advanced disease stage: stage IV///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tc_94///geo_accession: GSM1078983///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: clear cell///characteristics_ch1.2: advanced disease stage: stage IV///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: death///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Te_69///geo_accession: GSM1078984///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: endometrioid///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: death///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Te_77///geo_accession: GSM1078985///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: endometrioid///characteristics_ch1.2: advanced disease stage: stage II///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: death///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Te_78///geo_accession: GSM1078986///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: endometrioid///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Te_79///geo_accession: GSM1078987///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: endometrioid///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Te_84///geo_accession: GSM1078988///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: endometrioid///characteristics_ch1.2: advanced disease stage: stage II///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Te_87///geo_accession: GSM1078989///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: endometrioid///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Te_89///geo_accession: GSM1078990///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: endometrioid///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Te_90///geo_accession: GSM1078991///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: endometrioid///characteristics_ch1.2: advanced disease stage: stage IV///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Te_91///geo_accession: GSM1078992///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: endometrioid///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: death///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Te_92///geo_accession: GSM1078993///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: endometrioid///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Te_93///geo_accession: GSM1078994///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: endometrioid///characteristics_ch1.2: advanced disease stage: stage II///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tm_101///geo_accession: GSM1078995///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: mucinous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: death///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tm_102///geo_accession: GSM1078996///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: mucinous///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tm_106///geo_accession: GSM1078997///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: mucinous///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tm_107///geo_accession: GSM1078998///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: mucinous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tm_110///geo_accession: GSM1078999///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: mucinous///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tm_95///geo_accession: GSM1079000///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: mucinous///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tm_96///geo_accession: GSM1079001///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: mucinous///characteristics_ch1.2: advanced disease stage: stage II///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tm_97///geo_accession: GSM1079002///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: mucinous///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Tm_98///geo_accession: GSM1079003///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: mucinous///characteristics_ch1.2: advanced disease stage: stage II///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: death///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_11///geo_accession: GSM1079004///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_14///geo_accession: GSM1079005///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: death///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_15///geo_accession: GSM1079006///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_17///geo_accession: GSM1079007///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage I///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: death///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_19///geo_accession: GSM1079008///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: death///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_20///geo_accession: GSM1079009///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: death///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_21///geo_accession: GSM1079010///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_23///geo_accession: GSM1079011///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: death///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_24///geo_accession: GSM1079012///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_26///geo_accession: GSM1079013///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: death///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_28///geo_accession: GSM1079014///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_2///geo_accession: GSM1079015///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: death///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_31///geo_accession: GSM1079016///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_32///geo_accession: GSM1079017///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_34///geo_accession: GSM1079018///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_35///geo_accession: GSM1079019///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_36///geo_accession: GSM1079020///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_37///geo_accession: GSM1079021///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_39///geo_accession: GSM1079022///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_3///geo_accession: GSM1079023///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_41///geo_accession: GSM1079024///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_43///geo_accession: GSM1079025///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage II///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_45///geo_accession: GSM1079026///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage IV///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_46///geo_accession: GSM1079027///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage II///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_47///geo_accession: GSM1079028///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: non-recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_4///geo_accession: GSM1079029///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: death///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_5///geo_accession: GSM1079030///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage IV///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: death///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
title: Ts_8///geo_accession: GSM1079031///status: Public on Jan 01 2014///submission_date: Feb 06 2013///last_update_date: Jan 01 2014///type: RNA///channel_count: 1///source_name_ch1: primary surgical treatment///organism_ch1: Homo sapiens///characteristics_ch1: tissue: ovarian cancer cells///characteristics_ch1.1: tissue subtype: serous///characteristics_ch1.2: advanced disease stage: stage III///characteristics_ch1.3: recurrence status: recurrence///characteristics_ch1.4: survival/death: survival///treatment_protocol_ch1: Frozen rissues///growth_protocol_ch1: Frozen tissue samples were embedded, and sections were cut and mounted on slides. The slides were stained with H&E to ensure that at least 70
1
duplicates:
Length Class Mode
60 character character
|
An expression set
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.