GSE32063: High-risk ovarian cancer based on 126-gene expression...
In MetaGxOvarian: Transcriptomic Ovarian Cancer Datasets
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Description
High-grade serous ovarian cancers are heterogeneous not only in terms of clinical outcome but also at the molecular level. Our aim was to establish a novel risk classification system based on a gene expression signature for predicting overall survival, leading to suggesting novel therapeutic strategies for high-risk patients.In this large-scale cross-platform study of six microarray data sets consisting of 1,054 ovarian cancer patients, we developed a gene expression signature for predicting overall survival by applying elastic net and 10-fold cross-validation to a Japanese data set A (n = 260) and evaluated the signature in five other data sets. Subsequently, we investigated differences in the biological characteristics between high- and low-risk ovarian cancer groups.An elastic net analysis identified a 126-gene expression signature for predicting overall survival in patients with ovarian cancer using the Japanese data set A (multivariate analysis, P = 4 ?? 10(-20)). We validated its predictive ability with five other data sets using multivariate analysis (Tothill's data set, P = 1 ?? 10(-5); Bonome's data set, P = 0.0033; Dressman's data set, P = 0.0016; TCGA data set, P = 0.0027; Japanese data set B, P = 0.021). Through gene ontology and pathway analyses, we identified a significant reduction in expression of immune-response-related genes, especially on the antigen presentation pathway, in high-risk ovarian cancer patients.This risk classification based on the 126-gene expression signature is an accurate predictor of clinical outcome in patients with advanced stage high-grade serous ovarian cancer and has the potential to develop new therapeutic strategies for high-grade serous ovarian cancer patients.
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experimentData(eset):
Experiment data
Experimenter name: Yoshihara K, Tsunoda T, Shigemizu D, Fujiwara H et al. High-risk ovarian cancer based on 126-gene expression signature is uniquely characterized by downregulation of antigen presentation pathway. Clin Cancer Res 2012 Mar 1;18(5):1374-85.
Laboratory: Yoshihara, Tanaka 2012
Contact information:
Title: High-risk ovarian cancer based on 126-gene expression signature is uniquely characterized by downregulation of antigen presentation pathway.
URL:
PMIDs: 22241791
Abstract: A 255 word abstract is available. Use 'abstract' method.
Information is available on: preprocessing
notes:
platform_title:
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name vers
ion)
platform_shorttitle:
Agilent G4112F
platform_summary:
hgug4112a
platform_manufacturer:
Agilent
platform_distribution:
commercial
platform_accession:
GPL6480
version:
2015-09-22 19:58:23
featureData(eset):
An object of class 'AnnotatedDataFrame'
featureNames: A_23_P100001 A_23_P100011 ... A_32_P99902 (30936 total)
varLabels: probeset gene EntrezGene.ID best_probe
varMetadata: labelDescription
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assayData: 30936 features, 40 samples
Platform type:
Overall survival time-to-event summary (in years):
Call: survfit(formula = Surv(time, cens) ~ -1)
n events median 0.95LCL 0.95UCL
40.00 22.00 4.44 3.29 NA
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Available sample meta-data:
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alt_sample_name:
106 108 109R 110 111R 192 195R 196 197 198 200 203 205 206 207 213
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
222 224 226 229 230 231 274 277 278 280 281 282 283 284 285 286
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
287 288 289 291 292 294 297R 298R
1 1 1 1 1 1 1 1
sample_type:
tumor
40
histological_type:
ser
40
summarygrade:
high low
17 23
summarystage:
late
40
tumorstage:
3 4
31 9
substage:
b c NA's
3 28 9
grade:
2 3
23 17
pltx:
y
40
tax:
y
40
days_to_death:
Min. 1st Qu. Median Mean 3rd Qu. Max.
210 705 1155 1346 1792 3330
vital_status:
deceased living
22 18
debulking:
optimal suboptimal
19 21
uncurated_author_metadata:
title: serous ovarian cancer 106///geo_accession: GSM795125///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 15///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 26///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795125/GSM795125_s106.txt.gz///data_row_count: 41093///relation: Reanalysis of: GSM432223
1
title: serous ovarian cancer 108///geo_accession: GSM795126///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIb///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 37///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 37///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795126/GSM795126_s108.txt.gz///data_row_count: 41093///relation: Reanalysis of: GSM432225
1
title: serous ovarian cancer 109R///geo_accession: GSM795127///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 7///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 20///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795127/GSM795127_s109R.txt.gz///data_row_count: 41093///relation: Reanalysis of: GSM432226
1
title: serous ovarian cancer 110///geo_accession: GSM795128///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 97///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 97///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795128/GSM795128_s110.txt.gz///data_row_count: 41093///relation: Reanalysis of: GSM432228
1
title: serous ovarian cancer 111R///geo_accession: GSM795129///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 18///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 57///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795129/GSM795129_s111R.txt.gz///data_row_count: 41093///relation: Reanalysis of: GSM432229
1
title: serous ovarian cancer 192///geo_accession: GSM795130///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 20///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 27///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795130/GSM795130_s192.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 195R///geo_accession: GSM795131///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 6///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 40///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795131/GSM795131_s195R.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 196///geo_accession: GSM795132///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 28///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 37///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795132/GSM795132_s196.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 197///geo_accession: GSM795133///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIb///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 47///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 47///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795133/GSM795133_s197.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 198///geo_accession: GSM795134///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 8///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 24///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795134/GSM795134_s198.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 200///geo_accession: GSM795135///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 6///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 27///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795135/GSM795135_s200.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 203///geo_accession: GSM795136///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 26///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 46///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795136/GSM795136_s203.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 205///geo_accession: GSM795137///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 43///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 78///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795137/GSM795137_s205.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 206///geo_accession: GSM795138///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 21///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 87///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795138/GSM795138_s206.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 207///geo_accession: GSM795139///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 30///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 30///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795139/GSM795139_s207.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 213///geo_accession: GSM795140///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 15///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 35///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795140/GSM795140_s213.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 222///geo_accession: GSM795141///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 12///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 12///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795141/GSM795141_s222.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 224///geo_accession: GSM795142///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 11///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 16///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795142/GSM795142_s224.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 226///geo_accession: GSM795143///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 11///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 11///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795143/GSM795143_s226.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 229///geo_accession: GSM795144///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 9///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 9///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795144/GSM795144_s229.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 230///geo_accession: GSM795145///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 8///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 8///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795145/GSM795145_s230.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 231///geo_accession: GSM795146///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 7///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 7///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795146/GSM795146_s231.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 274///geo_accession: GSM795147///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 35///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 101///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795147/GSM795147_s274.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 277///geo_accession: GSM795148///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 73///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 109///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795148/GSM795148_s277.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 278///geo_accession: GSM795149///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 16///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 21///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795149/GSM795149_s278.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 280///geo_accession: GSM795150///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 68///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 68///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795150/GSM795150_s280.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 281///geo_accession: GSM795151///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 8///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 15///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795151/GSM795151_s281.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 282///geo_accession: GSM795152///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 82///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 82///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795152/GSM795152_s282.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 283///geo_accession: GSM795153///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 12///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 49///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795153/GSM795153_s283.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 284///geo_accession: GSM795154///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 111///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 111///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795154/GSM795154_s284.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 285///geo_accession: GSM795155///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 82///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 82///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795155/GSM795155_s285.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 286///geo_accession: GSM795156///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 8///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 22///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795156/GSM795156_s286.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 287///geo_accession: GSM795157///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 12///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 40///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795157/GSM795157_s287.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 288///geo_accession: GSM795158///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 9///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 24///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795158/GSM795158_s288.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 289///geo_accession: GSM795159///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIb///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 14///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 40///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795159/GSM795159_s289.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 291///geo_accession: GSM795160///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 15///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 48///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795160/GSM795160_s291.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 292///geo_accession: GSM795161///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 28///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 54///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795161/GSM795161_s292.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 294///geo_accession: GSM795162///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 49///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 70///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795162/GSM795162_s294.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 297R///geo_accession: GSM795163///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 2///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 24///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795163/GSM795163_s297R.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 298R///geo_accession: GSM795164///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 31///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 57///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795164/GSM795164_s298R.txt.gz///data_row_count: 41093///relation:
1
Value
An expression set
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Description Format Details Value
Description
High-grade serous ovarian cancers are heterogeneous not only in terms of clinical outcome but also at the molecular level. Our aim was to establish a novel risk classification system based on a gene expression signature for predicting overall survival, leading to suggesting novel therapeutic strategies for high-risk patients.In this large-scale cross-platform study of six microarray data sets consisting of 1,054 ovarian cancer patients, we developed a gene expression signature for predicting overall survival by applying elastic net and 10-fold cross-validation to a Japanese data set A (n = 260) and evaluated the signature in five other data sets. Subsequently, we investigated differences in the biological characteristics between high- and low-risk ovarian cancer groups.An elastic net analysis identified a 126-gene expression signature for predicting overall survival in patients with ovarian cancer using the Japanese data set A (multivariate analysis, P = 4 ?? 10(-20)). We validated its predictive ability with five other data sets using multivariate analysis (Tothill's data set, P = 1 ?? 10(-5); Bonome's data set, P = 0.0033; Dressman's data set, P = 0.0016; TCGA data set, P = 0.0027; Japanese data set B, P = 0.021). Through gene ontology and pathway analyses, we identified a significant reduction in expression of immune-response-related genes, especially on the antigen presentation pathway, in high-risk ovarian cancer patients.This risk classification based on the 126-gene expression signature is an accurate predictor of clinical outcome in patients with advanced stage high-grade serous ovarian cancer and has the potential to develop new therapeutic strategies for high-grade serous ovarian cancer patients.
Format
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 | experimentData(eset):
Experiment data
Experimenter name: Yoshihara K, Tsunoda T, Shigemizu D, Fujiwara H et al. High-risk ovarian cancer based on 126-gene expression signature is uniquely characterized by downregulation of antigen presentation pathway. Clin Cancer Res 2012 Mar 1;18(5):1374-85.
Laboratory: Yoshihara, Tanaka 2012
Contact information:
Title: High-risk ovarian cancer based on 126-gene expression signature is uniquely characterized by downregulation of antigen presentation pathway.
URL:
PMIDs: 22241791
Abstract: A 255 word abstract is available. Use 'abstract' method.
Information is available on: preprocessing
notes:
platform_title:
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name vers
ion)
platform_shorttitle:
Agilent G4112F
platform_summary:
hgug4112a
platform_manufacturer:
Agilent
platform_distribution:
commercial
platform_accession:
GPL6480
version:
2015-09-22 19:58:23
featureData(eset):
An object of class 'AnnotatedDataFrame'
featureNames: A_23_P100001 A_23_P100011 ... A_32_P99902 (30936 total)
varLabels: probeset gene EntrezGene.ID best_probe
varMetadata: labelDescription
|
Details
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 | assayData: 30936 features, 40 samples
Platform type:
Overall survival time-to-event summary (in years):
Call: survfit(formula = Surv(time, cens) ~ -1)
n events median 0.95LCL 0.95UCL
40.00 22.00 4.44 3.29 NA
---------------------------
Available sample meta-data:
---------------------------
alt_sample_name:
106 108 109R 110 111R 192 195R 196 197 198 200 203 205 206 207 213
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
222 224 226 229 230 231 274 277 278 280 281 282 283 284 285 286
1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
287 288 289 291 292 294 297R 298R
1 1 1 1 1 1 1 1
sample_type:
tumor
40
histological_type:
ser
40
summarygrade:
high low
17 23
summarystage:
late
40
tumorstage:
3 4
31 9
substage:
b c NA's
3 28 9
grade:
2 3
23 17
pltx:
y
40
tax:
y
40
days_to_death:
Min. 1st Qu. Median Mean 3rd Qu. Max.
210 705 1155 1346 1792 3330
vital_status:
deceased living
22 18
debulking:
optimal suboptimal
19 21
uncurated_author_metadata:
title: serous ovarian cancer 106///geo_accession: GSM795125///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 15///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 26///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795125/GSM795125_s106.txt.gz///data_row_count: 41093///relation: Reanalysis of: GSM432223
1
title: serous ovarian cancer 108///geo_accession: GSM795126///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIb///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 37///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 37///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795126/GSM795126_s108.txt.gz///data_row_count: 41093///relation: Reanalysis of: GSM432225
1
title: serous ovarian cancer 109R///geo_accession: GSM795127///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 7///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 20///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795127/GSM795127_s109R.txt.gz///data_row_count: 41093///relation: Reanalysis of: GSM432226
1
title: serous ovarian cancer 110///geo_accession: GSM795128///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 97///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 97///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795128/GSM795128_s110.txt.gz///data_row_count: 41093///relation: Reanalysis of: GSM432228
1
title: serous ovarian cancer 111R///geo_accession: GSM795129///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 18///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 57///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795129/GSM795129_s111R.txt.gz///data_row_count: 41093///relation: Reanalysis of: GSM432229
1
title: serous ovarian cancer 192///geo_accession: GSM795130///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 20///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 27///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795130/GSM795130_s192.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 195R///geo_accession: GSM795131///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 6///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 40///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795131/GSM795131_s195R.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 196///geo_accession: GSM795132///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 28///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 37///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795132/GSM795132_s196.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 197///geo_accession: GSM795133///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIb///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 47///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 47///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795133/GSM795133_s197.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 198///geo_accession: GSM795134///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 8///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 24///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795134/GSM795134_s198.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 200///geo_accession: GSM795135///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 6///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 27///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795135/GSM795135_s200.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 203///geo_accession: GSM795136///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 26///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 46///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795136/GSM795136_s203.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 205///geo_accession: GSM795137///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 43///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 78///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795137/GSM795137_s205.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 206///geo_accession: GSM795138///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 21///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 87///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795138/GSM795138_s206.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 207///geo_accession: GSM795139///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 30///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 30///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795139/GSM795139_s207.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 213///geo_accession: GSM795140///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 15///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 35///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795140/GSM795140_s213.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 222///geo_accession: GSM795141///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 12///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 12///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795141/GSM795141_s222.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 224///geo_accession: GSM795142///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 11///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 16///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795142/GSM795142_s224.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 226///geo_accession: GSM795143///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 11///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 11///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795143/GSM795143_s226.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 229///geo_accession: GSM795144///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 9///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 9///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795144/GSM795144_s229.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 230///geo_accession: GSM795145///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 8///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 8///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795145/GSM795145_s230.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 231///geo_accession: GSM795146///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 7///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 7///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795146/GSM795146_s231.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 274///geo_accession: GSM795147///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 35///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 101///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795147/GSM795147_s274.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 277///geo_accession: GSM795148///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 73///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 109///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795148/GSM795148_s277.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 278///geo_accession: GSM795149///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 16///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 21///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795149/GSM795149_s278.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 280///geo_accession: GSM795150///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 68///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 68///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795150/GSM795150_s280.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 281///geo_accession: GSM795151///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 8///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 15///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795151/GSM795151_s281.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 282///geo_accession: GSM795152///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 82///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 82///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795152/GSM795152_s282.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 283///geo_accession: GSM795153///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 12///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 49///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795153/GSM795153_s283.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 284///geo_accession: GSM795154///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 111///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 111///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795154/GSM795154_s284.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 285///geo_accession: GSM795155///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 82///characteristics_ch1.7: rec (1): 0///characteristics_ch1.8: os (m): 82///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795155/GSM795155_s285.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 286///geo_accession: GSM795156///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 8///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 22///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795156/GSM795156_s286.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 287///geo_accession: GSM795157///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 12///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 40///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795157/GSM795157_s287.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 288///geo_accession: GSM795158///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 9///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 24///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795158/GSM795158_s288.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 289///geo_accession: GSM795159///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIb///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 14///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 40///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795159/GSM795159_s289.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 291///geo_accession: GSM795160///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 15///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 48///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795160/GSM795160_s291.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 292///geo_accession: GSM795161///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 28///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 54///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795161/GSM795161_s292.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 294///geo_accession: GSM795162///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 3///characteristics_ch1.2: Stage: IIIc///characteristics_ch1.3: surgery status: optimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 49///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 70///characteristics_ch1.9: death (1): 0///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795162/GSM795162_s294.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 297R///geo_accession: GSM795163///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 2///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 24///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795163/GSM795163_s297R.txt.gz///data_row_count: 41093///relation:
1
title: serous ovarian cancer 298R///geo_accession: GSM795164///status: Public on Mar 01 2012///submission_date: Sep 12 2011///last_update_date: Mar 01 2012///type: RNA///channel_count: 1///source_name_ch1: high-grade serous ovarian cancer///organism_ch1: Homo sapiens///characteristics_ch1: tissue: tumor///characteristics_ch1.1: grading: 2///characteristics_ch1.2: Stage: IV///characteristics_ch1.3: surgery status: suboptimal///characteristics_ch1.4: taxane: 1///characteristics_ch1.5: platinum: 1///characteristics_ch1.6: pfs (m): 31///characteristics_ch1.7: rec (1): 1///characteristics_ch1.8: os (m): 57///characteristics_ch1.9: death (1): 1///molecule_ch1: total RNA///extract_protocol_ch1: Total RNA was extracted from tissue samples using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's recommendations. RNA was examined with a 2100 Bioanalyzer (Agilent Technologies Inc., Palo Alto, CA, USA) using an RNA 6000 Nano LabChip (Agilent Technologies)///label_ch1: Cy3///label_protocol_ch1: Cyanine-3 (Cy3) labeled cRNA was prepared from 0.5 ug RNA using the Quick Amp Labering Kit, one-color (Agilent Technologies) according to the manufacturer's instructions, followed by RNAeasy column purification (QIAGEN, Valencia, CA).///taxid_ch1: 9606///hyb_protocol: Cy3-labeled cRNAs (1.65 g) were hybridized for 17 hours at 65C to an Agilent Whole Human Genome Oligo Microarray in a rotating Agilent hybridization oven.///scan_protocol: The hybridized microarray was washed and then scanned in Cy3 channel with the Agilent DNA Microarray Scanner (model G2565AA).///data_processing: Signal intensity per spot was generated from the scanned image with Feature Extraction Software ver.9.1 (Agilent Technologies) in the default settings.///platform_id: GPL6480///contact_name: Kosuke,,Yoshihara///contact_email: yoshikou@med.niigata-u.ac.jp///contact_department: Obstetrics and Gynecology///contact_institute: Niigata University///contact_address: 1-757 Asahimachi-dori///contact_city: Niigata///contact_zip.postal_code: 951-8510///contact_country: Japan///supplementary_file: ftp://ftp.ncbi.nih.gov/pub/geo/DATA/supplementary/samples/GSM795nnn/GSM795164/GSM795164_s298R.txt.gz///data_row_count: 41093///relation:
1
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