UMI4Cats: UMI4Cats: Processing, analysis and visualization of UMI-4C chromatin contact data

UMI-4C is a technique that allows characterization of 3D chromatin interactions with a bait of interest, taking advantage of a sonication step to produce unique molecular identifiers (UMIs) that help remove duplication bias, thus allowing a better differential comparsion of chromatin interactions between conditions. This package allows processing of UMI-4C data, starting from FastQ files provided by the sequencing facility. It provides two statistical methods for detecting differential contacts and includes a visualization function to plot integrated information from a UMI-4C assay.

Package details

AuthorMireia Ramos-Rodriguez [aut, cre] (<>), Marc Subirana-Granes [aut]
Bioconductor views Alignment Coverage Normalization Preprocessing QualityControl Sequencing Visualization
MaintainerMireia Ramos-Rodriguez <>
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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UMI4Cats documentation built on Dec. 31, 2020, 2:01 a.m.