UMI-4C is a technique that allows characterization of 3D chromatin interactions with a bait of interest, taking advantage of a sonication step to produce unique molecular identifiers (UMIs) that help remove duplication bias, thus allowing a better differential comparsion of chromatin interactions between conditions. This package allows processing of UMI-4C data, starting from FastQ files provided by the sequencing facility. It provides two statistical methods for detecting differential contacts and includes a visualization function to plot integrated information from a UMI-4C assay.
|Author||Mireia Ramos-Rodriguez [aut, cre] (<https://orcid.org/0000-0001-8083-2445>), Marc Subirana-Granes [aut]|
|Bioconductor views||Alignment Coverage Normalization Preprocessing QualityControl Sequencing Visualization|
|Maintainer||Mireia Ramos-Rodriguez <firstname.lastname@example.org>|
|Package repository||View on Bioconductor|
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