derfinder: Annotation-agnostic differential expression analysis of RNA-seq data at base-pair resolution via the DER Finder approach

This package provides functions for annotation-agnostic differential expression analysis of RNA-seq data. Two implementations of the DER Finder approach are included in this package: (1) single base-level F-statistics and (2) DER identification at the expressed regions-level. The DER Finder approach can also be used to identify differentially bounded ChIP-seq peaks.

Package details

AuthorLeonardo Collado-Torres [aut, cre] (<>), Alyssa C. Frazee [ctb], Andrew E. Jaffe [aut] (<>), Jeffrey T. Leek [aut, ths] (<>)
Bioconductor views ChIPSeq Coverage DifferentialExpression DifferentialPeakCalling ImmunoOncology RNASeq Sequencing Software
MaintainerLeonardo Collado-Torres <>
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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derfinder documentation built on Dec. 20, 2020, 2 a.m.