genesToBarcodes: Extracts Tumor Sample Barcodes where the given genes are...

Description Usage Arguments Value Examples

View source: R/genesToBarcodes.R

Description

Extracts Tumor Sample Barcodes where the given genes are mutated.

Usage

1
genesToBarcodes(maf, genes = NULL, justNames = FALSE, verbose = TRUE)

Arguments

maf

an MAF object generated by read.maf

genes

Hogo_Symbol for which sample names to be extracted.

justNames

if TRUE, just returns samples names instead of summarized tables.

verbose

Default TRUE

Value

list of data.tables with samples in which given genes are mutated.

Examples

1
2
3
laml.maf <- system.file("extdata", "tcga_laml.maf.gz", package = "maftools")
laml <- read.maf(maf = laml.maf)
genesToBarcodes(maf = laml, genes = 'DNMT3A')

Example output

-Reading
-Validating
-Silent variants: 475 
-Summarizing
-Processing clinical data
--Missing clinical data
-Finished in 0.532s elapsed (0.440s cpu) 
$DNMT3A
    Tumor_Sample_Barcode Frame_Shift_Del Frame_Shift_Ins In_Frame_Del
 1:         TCGA-AB-2912               0               1            0
 2:         TCGA-AB-2822               1               0            0
 3:         TCGA-AB-2839               1               2            0
 4:         TCGA-AB-2863               0               0            1
 5:         TCGA-AB-2908               2               0            0
 6:         TCGA-AB-2938               3               0            0
 7:         TCGA-AB-2861               0               0            0
 8:         TCGA-AB-2925               0               0            0
 9:         TCGA-AB-2949               2               0            0
10:         TCGA-AB-2891               0               0            0
11:         TCGA-AB-2830               1               1            0
12:         TCGA-AB-2864               0               1            0
13:         TCGA-AB-2988               0               1            0
14:         TCGA-AB-2887               0               0            0
15:         TCGA-AB-2898               0               1            1
16:         TCGA-AB-2945               1               1            0
17:         TCGA-AB-2955               1               0            0
18:         TCGA-AB-2968               1               1            0
19:         TCGA-AB-2895               0               0            0
20:         TCGA-AB-2966               1               0            0
21:         TCGA-AB-2993               1               1            0
22:         TCGA-AB-2859               2               1            0
23:         TCGA-AB-2931               0               0            0
24:         TCGA-AB-2965               1               1            0
25:         TCGA-AB-2967               0               3            0
26:         TCGA-AB-2802               0               2            0
27:         TCGA-AB-2867               0               0            0
28:         TCGA-AB-2928               1               0            0
29:         TCGA-AB-2869               0               1            0
30:         TCGA-AB-2916               0               0            0
31:         TCGA-AB-2919               0               0            0
32:         TCGA-AB-2934               0               1            0
33:         TCGA-AB-2818               0               0            0
34:         TCGA-AB-2833               0               0            0
35:         TCGA-AB-2987               0               1            0
36:         TCGA-AB-2851               1               0            0
37:         TCGA-AB-2853               0               0            0
38:         TCGA-AB-2974               0               1            0
39:         TCGA-AB-2816               0               0            0
40:         TCGA-AB-2824               0               1            0
41:         TCGA-AB-2884               0               1            0
42:         TCGA-AB-2981               0               1            0
43:         TCGA-AB-2809               0               0            0
44:         TCGA-AB-2825               0               1            0
45:         TCGA-AB-2896               0               2            0
46:         TCGA-AB-2947               0               1            0
47:         TCGA-AB-2873               1               0            0
48:         TCGA-AB-2975               0               0            0
    Tumor_Sample_Barcode Frame_Shift_Del Frame_Shift_Ins In_Frame_Del
    In_Frame_Ins Missense_Mutation Nonsense_Mutation Splice_Site total
 1:            0                15                 1           2    19
 2:            0                14                 1           1    17
 3:            0                13                 1           0    17
 4:            0                14                 1           0    16
 5:            0                11                 3           0    16
 6:            0                13                 0           0    16
 7:            0                12                 1           2    15
 8:            1                14                 0           0    15
 9:            0                12                 0           1    15
10:            0                12                 0           2    14
11:            1                10                 0           0    13
12:            0                10                 1           1    13
13:            0                11                 0           1    13
14:            0                12                 0           0    12
15:            0                 8                 0           2    12
16:            0                10                 0           0    12
17:            1                 9                 1           0    12
18:            0                 8                 1           1    12
19:            0                 9                 0           2    11
20:            0                10                 0           0    11
21:            1                 6                 2           0    11
22:            0                 7                 0           0    10
23:            0                 8                 0           2    10
24:            1                 7                 0           0    10
25:            0                 3                 2           2    10
26:            0                 7                 0           0     9
27:            0                 8                 1           0     9
28:            0                 7                 1           0     9
29:            1                 5                 1           0     8
30:            0                 6                 1           1     8
31:            0                 8                 0           0     8
32:            1                 5                 0           1     8
33:            0                 5                 0           2     7
34:            0                 6                 1           0     7
35:            0                 6                 0           0     7
36:            0                 4                 1           0     6
37:            1                 5                 0           0     6
38:            0                 5                 0           0     6
39:            0                 5                 0           0     5
40:            0                 4                 0           0     5
41:            0                 4                 0           0     5
42:            1                 2                 0           0     4
43:            0                 2                 1           0     3
44:            0                 1                 0           1     3
45:            0                 1                 0           0     3
46:            0                 2                 0           0     3
47:            0                 1                 0           0     2
48:            0                 1                 1           0     2
    In_Frame_Ins Missense_Mutation Nonsense_Mutation Splice_Site total

maftools documentation built on Feb. 6, 2021, 2 a.m.