compareSignatures: Compares identified denovo mutational signatures to known...

Description Usage Arguments Details Value See Also

View source: R/compareSignatures.R

Description

Takes results from extractSignatures and compares them known COSMIC signatures. Two COSMIC databases are used for comparisons - "legacy" which includes 30 signaures, and "SBS" - which includes updated/refined 65 signatures

Usage

1
compareSignatures(nmfRes, sig_db = "legacy", verbose = TRUE)

Arguments

nmfRes

results from extractSignatures

sig_db

can be legacy or SBS. Default legacy

verbose

Default TRUE

Details

SBS signature database was obtained from https://www.synapse.org/#!Synapse:syn11738319.7

Value

list containing cosine smilarities, aetiologies if available, and best match.

See Also

trinucleotideMatrix extractSignatures plotSignatures


maftools documentation built on Feb. 6, 2021, 2 a.m.