Down: The down syndrome data

DownR Documentation

The down syndrome data

Description

Data on N=11 studies from the systematic review that examined the screening accuracy of shortened humerus and shortened femur of the fetus markers (two out of seven ultrasonographic markers or their combination in detecting Down syndrome in Smith-Bindman et al., 2001).

Format

A data frame with 11 observations on the following 8 variables.

down_n_00

the number of the test results in the diseased where the shortened humerus outcome is negative and the shortened femur outcome is negative

down_n_01

the number of the test results in the diseased where the shortened humerus outcome is negative and the shortened femur outcome is positive

down_n_10

the number of the test results in the diseased where the shortened humerus outcome is positive and the shortened femur outcome is negative

down_n_11

the number of the test results in the diseased where the shortened humerus outcome is positive and the shortened femur outcome is positive

nodown_n_00

the number of the test results in the non-diseased where the shortened humerus outcome is negative and the shortened femur outcome is negative

nodown_n_01

the number of the test results in the non-diseased where the shortened humerus outcome is negative and the shortened femur outcome is positive

nodown_n_10

the number of the test results in the non-diseased where the shortened humerus outcome is positive and the shortened femur outcome is negative

nodown_n_11

the number of the test results in the non-diseased where the shortened humerus outcome is positive and the shortened femur outcome is positive

References

Smith-Bindman R, Hosmer W, Feldstein V et al. Second-trimester ultrasound to detect fetuses with down syndrome: A meta-analysis (2001). Journal of the American Medical Association, 285(8): 1044-1055.


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