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ConsensusClustering=function(Data,ClusterNo=NULL,PlotIt=FALSE,PlotConsensus=FALSE,...){
# INPUT
# Data[1:n,1:d] Data set with n observations and d features
# ClusterNo Number of clusters to search for
#
# OPTIONAL
# PlotIt Boolean. Decision to plot or not
# PlotConsensus: FALSE, NULL, "png", "pdf", or "pngBMP".
# OUTPUT
# Cls[1:n] Clustering of data
# Object Object of ConsensusClustering
#
# Author: MT 07/26
if (!requireNamespace("ConsensusClusterPlus", quietly = TRUE)) {
warning(paste(
"Package 'ConsensusClusterPlus' is required.",
"Install it with BiocManager::install('ConsensusClusterPlus').") )
return(
list(
Cls = rep(1, nrow(Data)),
Object = "Subordinate clustering package (cluster) is missing although its imported in ADPclust.
Please install the package which is defined in 'Suggests'."
)
)
}
Data = as.matrix(Data)
if (!is.numeric(Data)) {
stop("Data must be numeric.", call. = FALSE)
}
if (anyNA(Data) || any(!is.finite(Data))) {
stop("Data must not contain NA, NaN, or infinite values.", call. = FALSE)
}
if (!is.null(ClusterNo)) {
if (length(ClusterNo) != 1L || ClusterNo < 2 || ClusterNo %% 1 != 0) {
stop("ClusterNo must be a single integer greater than 1.", call. = FALSE)
}
ClusterNo = as.integer(ClusterNo)
}
# ConsensusClusterPlus expects features in rows
# and observations in columns.
CCPData = t(Data)
if (is.null(ClusterNo)) {
return(
ConsensusClusterPlus::ConsensusClusterPlus(
d = CCPData,
plot = PlotConsensus,
...
)
)
}
CA = ConsensusClusterPlus::ConsensusClusterPlus(
d = CCPData,
maxK = ClusterNo,
plot = PlotConsensus,
...
)
Cls = CA[[ClusterNo]]$consensusClass
if (exists("ClusterRename", mode = "function")) {
Cls = ClusterRename(Cls, Data)
}
if (isTRUE(PlotIt)) {
if (!exists("ClusterPlotMDS", mode = "function")) {
warning("ClusterPlotMDS() was not found.")
} else {
ClusterPlotMDS(Data, Cls)
}
}
list(
Cls = Cls,
Object = CA
)
}
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