R/testIndSpearman.R

Defines functions testIndSpearman

Documented in testIndSpearman

testIndSpearman <- function(target, dataset, xIndex, csIndex, wei = NULL, statistic = FALSE, univariateModels = NULL, 
                            hash = FALSE, stat_hash = NULL, pvalue_hash = NULL)  {
  # TESTINDFISHER Fisher Conditional Independence Test for continous class variables
  # PVALUE = TESTINDFISHER(Y, DATA, XINDEX, CSINDEX)
  # This test provides a p-value PVALUE for the NULL hypothesis H0 which is
  # X is independent by TARGET given CS. The pvalue is calculated following
  # Fisher's method (see reference below)
  # This method requires the following inputs
  #   TARGET: a numeric vector containing the values of the target (continuous) variable. 
  #   Its support can be R or any number betweeen 0 and 1, i.e. it contains proportions.
  #   DATASET: a numeric data matrix containing the variables for performing the test. They can be only be continuous variables. 
  #   XINDEX: the index of the variable whose association with the target we want to test. 
  #   CSINDEX: the indices if the variable to condition on. 
  # this method returns: the pvalue PVALUE, the statistic STAT.
  # Copyright 2012 Vincenzo Lagani and Ioannis Tsamardinos
  # R Implementation by Giorgos Athineou (10/2013)
  # if the test cannot performed succesfully these are the returned values
  pvalue <- log(1);
  stat <- 0;
  
  if ( !is.list(target) ) {
  csIndex[which(is.na(csIndex))] = 0;
  
  if( hash ) {
    csIndex2 <- csIndex[which(csIndex!=0)]
    csIndex2 <- sort(csIndex2)
    xcs <- c(xIndex,csIndex2)
    key <- paste(as.character(xcs) , collapse=" ");
    if(is.null(stat_hash[key]) == FALSE)  {
      stat <- stat_hash[key];
      pvalue <- pvalue_hash[key];
      results <- list(pvalue = pvalue, stat = stat, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
      return(results);
    }
  }
  #if the xIndex is contained in csIndex, x does not bring any new
  #information with respect to cs
  if ( !is.na( match(xIndex, csIndex) ) )   {
    if ( hash )  {    #update hash objects
      stat_hash[key] <- 0;   #.set(stat_hash , key , 0)
      pvalue_hash[key] <- log(1);   #.set(pvalue_hash , key , 1)
    }
    results <- list(pvalue = log(1), stat = 0, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
    return(results);
  }
  
  #check input validity
  if( any(xIndex < 0) || any(csIndex < 0) )  {
    message(paste("error in testIndFisher : wrong input of xIndex or csIndex"))
    results <- list(pvalue = pvalue, stat = 0, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
    return(results);
  }
  
  xIndex <- unique(xIndex);
  csIndex <- unique(csIndex);
  x <- dataset[ , xIndex];
  cs <- dataset[ , csIndex, drop = FALSE];
  n <- length(target)
  #That means that the x variable does not add more information to our model due to an exact copy of this in the cs, so it is independent from the target
  if ( length(cs) != 0 )  {
    if ( is.null(dim(cs)[2]) )  {   #cs is a vector
      if ( identical(x, cs) ) {   #if(!any(x == cs) == FALSE)
        if ( hash )  {   #update hash objects
          stat_hash[key] <- 0;#.set(stat_hash , key , 0)
          pvalue_hash[key] <- log(1);#.set(pvalue_hash , key , 1)
        }
        results <- list(pvalue = log(1), stat = 0, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
        return(results);
      }
    } else { #more than one var
      for (col in 1:dim(cs)[2]) {
        if ( identical(x, cs[,col]) )  {    #if(!any(x == cs) == FALSE)
          if ( hash )  {   #update hash objects
            stat_hash[key] <- 0;    #.set(stat_hash , key , 0)
            pvalue_hash[key] <- log(1);     #.set(pvalue_hash , key , 1)
          }
          results <- list(pvalue = log(1), stat = 0, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
          return(results);
        }
      }
    }
  }
#trycatch for dealing with errors
res <- tryCatch(
{
  #if the conditioning set (cs) is empty, we use a simplified formula
  if ( length(cs) == 0 )  {
    if ( !is.null(univariateModels) )   {
      pvalue <- univariateModels$pvalue[[xIndex]];
      stat <- univariateModels$stat[[xIndex]];
      results <- list(pvalue = pvalue, stat = stat, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
      return(results);
    }
    #compute the correlation coefficient between x,target directly
    stat <- cor(x, target);
	  
  } else {
    #perform the test with the cs
     tmpm <- cbind(x, target, cs);    
     corrMatrix <- cor(tmpm);   
     xyIdx <- 1:2;
     csIdx <- 3:(NCOL(cs) + 2); #or csIdx = 3;    
     residCorrMatrix <- (corrMatrix[xyIdx, xyIdx]) - as.matrix(corrMatrix[xyIdx, csIdx])%*%(solve( as.matrix(corrMatrix[csIdx, csIdx]) , rbind(corrMatrix[csIdx, xyIdx])) );
     stat <- abs(residCorrMatrix[1,2] / sqrt(residCorrMatrix[1,1] * residCorrMatrix[2,2]));
  }
  #lets calculate the p-value
  z <- 0.5 * log( (1 + stat) / (1 - stat) );
  dof <- n - NCOL(cs) - 3; #degrees of freedom
  w <- sqrt(dof) * z / 1.029563;
  pvalue <- log(2) + pt(-abs(w), dof, log.p = TRUE) ;  # ?dt for documentation
  #last error check
  if ( is.na(pvalue) || is.na(stat) )  {
    pvalue <- log(1);
    stat <- 0;
  } else {
    #update hash objects
    if( hash )  {
      stat_hash[key] <- stat;       #.set(stat_hash , key , stat)
      pvalue_hash[key] <- pvalue;     #.set(pvalue_hash , key , pvalue)
    }
  }
  #testerrorcaseintrycatch(4);
  results <- list(pvalue = pvalue, stat = abs(w), stat_hash=stat_hash, pvalue_hash=pvalue_hash);
  return(results);
},
error = function(cond) {
  #error case (we are pretty sure that the only error case is when x,cs are highly correlated and the inversion of the matrix is not possible)
  pvalue <- log(1);
  stat <- 0;
  results <- list(pvalue = pvalue, stat = stat, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
  return(results);
},
finally = {}
)    

  
##################################  

            ## meta-analytic approach

##################################
	
  
} else { 


  D = length(target)
  nu = numeric(D)
  aa <- list()

  for ( i in 1:D ) {
   
  targ = target[[ i ]]
  data = dataset[[ i ]]  
  #if the test cannot performed succesfully these are the returned values
  n = nu[i] = length( targ )
  csIndex[which(is.na(csIndex))] = 0;
  
  if( hash )  {
    csIndex2 <- csIndex[which(csIndex!=0)]
    csIndex2 <- sort(csIndex2)
    xcs <- c(xIndex, csIndex2)
    key <- paste(as.character(xcs) , collapse=" ");
    if(is.null(stat_hash[key]) == FALSE)  {
      stat <- stat_hash[key];
      pvalue <- pvalue_hash[key];
      aa[[ i ]] <- list(pvalue = pvalue, z = z, stat = stat, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
    }
  }
  if ( !is.na( match(xIndex, csIndex) ) ) {
    if ( hash )  {      #update hash objects
      stat_hash[key] <- 0;      #.set(stat_hash , key , 0)
      pvalue_hash[key] <- log(1);         #.set(pvalue_hash , key , 1)
    }
    aa[[ i ]] <- list(pvalue = log(1), z = 0, stat = 0, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
  }
  #check input validity
  if( any(xIndex < 0) || any(csIndex < 0) )  {
    message(paste("error in testIndFisher : wrong input of xIndex or csIndex"))
    aa[[ i ]] <- list(pvalue = pvalue, z = 0, stat = 0, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
  }
  
  xIndex <- unique(xIndex);
  csIndex <- unique(csIndex);
  x <- data[ , xIndex];
  cs <- data[ , csIndex, drop = FALSE];
  #That means that the x variable does not add more information to our model due to an exact copy of this in the cs, so it is independent from the target
  if ( length(cs) != 0 )   {
    if ( is.null( dim(cs )[2]) )  {     #cs is a vector
      if (any(x != cs) == FALSE)  {     #if(!any(x == cs) == FALSE)
        if ( hash )  {      #update hash objects
          stat_hash[key] <- 0;          #.set(stat_hash , key , 0)
          pvalue_hash[key] <- log(1);       #.set(pvalue_hash , key , 1)
        }
        aa[[ i ]] <- list(pvalue = log(1), z = 0, stat = 0, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
      }
    } else {         #more than one var
      for ( col in 1:ncol(cs) ) {
        if(any(x != cs[, col]) == FALSE)  {      #if(!any(x == cs) == FALSE)
          if( hash )  {     #update hash objects
            stat_hash[key] <- 0;            #.set(stat_hash , key , 0)
            pvalue_hash[key] <- log(1);           #.set(pvalue_hash , key , 1)
          }
          aa[[ i ]] <- list(pvalue = log(1), z = 0, stat = 0, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
        }
      }
    }
  }
  #if x or target is constant then there is no point to perform the test
  if( Rfast::Var(x) == 0 )  {
    if( hash )  {           #update hash objects
      stat_hash[key] <- 0;           #.set(stat_hash , key , 0)
      pvalue_hash[key] <- log(1);       #.set(pvalue_hash , key , 1)
    }
    aa[[ i ]] <- list(pvalue = log(1), z = 0, stat = 0, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
  }
  #remove constant columns of cs
  cs <- cs[, apply(cs, 2, var, na.rm=TRUE) != 0 ]
  
aa[[ i ]] <- tryCatch(
{
  #if the conditioning set (cs) is empty, we use a simplified formula
  if (length(cs) == 0)  {
    if ( !is.null(univariateModels) )  {
      pvalue <- univariateModels$pvalue[[xIndex]];
      stat <- univariateModels$stat[[xIndex]];
      results <- list(pvalue = pvalue, stat = stat, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
      return(results);
    }
    #compute the correlation coefficient between x, target directly
    stat <- cor(x, targ);

  } else{
     #perform the test with the cs
      tmpm = cbind(x, targ, cs);     
      corrMatrix = cor(tmpm);     
      xyIdx = 1:2;
      csIdx = 3:(ncol(as.matrix(cs))+2); #or csIdx = 3;     
      residCorrMatrix = (corrMatrix[xyIdx, xyIdx]) - as.matrix(corrMatrix[xyIdx, csIdx])%*%(solve( as.matrix(corrMatrix[csIdx, csIdx]) , rbind(corrMatrix[csIdx, xyIdx])) );
      stat = abs(residCorrMatrix[1,2] / sqrt(residCorrMatrix[1,1] * residCorrMatrix[2,2]));
  }
  #comparing against the Student's t distribution
  z = 0.5 * log( (1 + stat) / (1 - stat) );
  dof = n - dim(cs)[2] - 3; #degrees of freedom
  w = sqrt(dof) * abs(z) / 1.029563; ## standard errot for Spearman
  pvalue = log(2) + pt(-w, dof, log.p = TRUE) ;  # ?dt for documentation
  #last error check
  if ( is.na(pvalue) || is.na(stat) ) {
    pvalue = log(1);
    stat = 0;
  } else {
    #update hash objects
    if( hash ) {
      stat_hash[key] <- stat;     #.set(stat_hash , key , stat)
      pvalue_hash[key] <- pvalue;       #.set(pvalue_hash , key , pvalue)
    }
  }
  #testerrorcaseintrycatch(4);
  list(pvalue = pvalue, z = z, nu = n, stat = w, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
},
error=function(cond) {
  #error case (we are pretty sure that the only error case is when x,cs are highly correlated and the inversion of the matrix is not possible)
  pvalue = log(1);
  stat = 0;
  list(pvalue = pvalue, z = z, nu = n, stat = stat, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
 },
finally={}
) 
  
}

  if  ( !statistic ) {
    
	  pva <- numeric(D) 
    for ( j in 1:D )   pva[j] <- -2 * aa[[ j ]]$pvalue
    stat <- sum(pva)
    pvalue <- pchisq( stat, 2 * D, lower.tail = FALSE, log.p = TRUE ) 
  
  } else {
    sta <- se <- numeric(D) 
	  cisa <- ncol(cs)
    for ( j in 1:D )  {
	    sta[j] <- aa[[ j ]]$z
	    se[j] <- 1 / sqrt(aa[ j ]$nu -  cisa - 3 ) 
    }
	  sse <- sum(se)
	  stat <- (sta * se) / sqrt( sse )
	  pvalue <- log(2) + pnorm( -abs(stat) / 1.029563 , log.p = TRUE )
  }
  
  if ( hash ) {
    stat_hash[key] <- stat
    pvalue_hash[key] <- pvalue  
  }

 res <- list(pvalue = pvalue, stat = stat, stat_hash=stat_hash, pvalue_hash=pvalue_hash);
}
  
 res
}

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MXM documentation built on Aug. 25, 2022, 9:05 a.m.