albAge | Concentration of albumin according to age. |
alpha1AGage | Concentration of alpha1-acid glycoprotein according to age. |
Cladu | Clearance of the unbound fraction of a specific molecule for... |
Clch.Allo | Paediatric clearance according to the allometry adjustment... |
Clch.Linear | Paediatric clearance according to the linear adjustment (LA)... |
Clch.Mat | Paediatric clearance according to the maturation adjustment... |
Clchu | Clearance of the unbound fraction of a specific molecule for... |
concAd | Concentration of a specific molecule in plasma for the adult... |
concCh | Concentration of a specific molecule in plasma for the... |
dfped-package | Extrapolation and Bridging of Adult Information in Early... |
doseChoice | Choice of the next given dose level. |
doseRange | Dose-range for the paediatric population according to adult... |
Fch | Paediatric bioavailability according to age. |
fuCh | Unbound fraction of the molecule in the plasma for children. |
KCYP1A2 | Fraction of adult CYP1A2 abundance according to age. |
KCYP2B6 | Fraction of adult CYP2B6 abundance according to age. |
KCYP2C18_19 | Fraction of adult CYP2C18/CYP2C19 abundance according to age. |
KCYP2C8 | Fraction of adult CYP2C8 abundance according to age. |
KCYP2C9 | Fraction of adult CYP2C9 abundance according to age. |
KCYP2D6 | Fraction of adult CYP2D6 abundance according to age. |
KCYP2E1 | Fraction of adult CYP2E1 abundance according to age. |
KCYP3A | Fraction of adult CYP3A abundance according to age. |
KCYP3A4_5 | Fraction of adult CYP3A4/CYP3A5 abundance according to age. |
kickoffControl | Control for presence of at least toxicities and efficacies... |
metaPhase | Meta-analysis function of dose-finding studies proposed by... |
priorChoice | Decision function for the choice of variance (sigmaHI or... |
sigmaEss | The variance of the effective sample size (ESS). |
sigmaHI | Compute the informative prior variance for the adaptive... |
sigmaLI | Compute the least informative prior variance for the adaptive... |
simu | A simulation of a single dose-finding trials in paediatrics. |
simulation | Simulate one or "n" dose-finding trials in paediatrics. |
skeleton | Build a working model. |
waic | Function for the Watanabe-Akaike information criteria (WAIC) |
weightCYPsum | Proportion of the molecule metabolised by the CYPs for a... |
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