KCYP2C8: Fraction of adult CYP2C8 abundance according to age.
In dfped: Extrapolation and Bridging of Adult Information in Early Phase Dose-Finding Paediatrics Studies
Description
Usage
Arguments
Author(s)
References
See Also
Examples
Description
Compute the value of the fraction of adult CYP2C8 abundance according to the children age. It is described by a hyperbolic function.
Usage
1
KCYP2C8(age)
Arguments
age
The age of children.
Author(s)
Artemis Toumazi artemis.toumazi@gmail.com,
Caroline Petit caroline.petit@crc.jussieu.fr,
Sarah Zohar sarah.zohar@inserm.fr
References
Petit, C., et al, (2016) Unified approach for extrapolation and bridging of adult information in early phase dose-finding paediatric studies, Statistical Methods in Medical Research, <doi:10.1177/0962280216671348>.
Johnson T., Rostami-Hodjegan A. and Tucker G. (2006) Prediction of clearance of eleven drugs and associated variability in neonates, infants and children, Clin. Pharmacokinet., 45:931-956.
See Also
KCYP1A2, KCYP2B6, KCYP2C9, KCYP2C18_19, KCYP2D6, KCYP2E1,
KCYP3A4_5, KCYP3A
Examples
1
2
age <- 2
KCYP2C8(age)
dfped documentation built on May 2, 2019, 8:36 a.m.
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Description Usage Arguments Author(s) References See Also Examples
Description
Compute the value of the fraction of adult CYP2C8 abundance according to the children age. It is described by a hyperbolic function.
Usage
1 | KCYP2C8(age)
|
Arguments
age |
The age of children. |
Author(s)
Artemis Toumazi artemis.toumazi@gmail.com, Caroline Petit caroline.petit@crc.jussieu.fr, Sarah Zohar sarah.zohar@inserm.fr
References
Petit, C., et al, (2016) Unified approach for extrapolation and bridging of adult information in early phase dose-finding paediatric studies, Statistical Methods in Medical Research, <doi:10.1177/0962280216671348>.
Johnson T., Rostami-Hodjegan A. and Tucker G. (2006) Prediction of clearance of eleven drugs and associated variability in neonates, infants and children, Clin. Pharmacokinet., 45:931-956.
See Also
KCYP1A2, KCYP2B6, KCYP2C9, KCYP2C18_19, KCYP2D6, KCYP2E1,
KCYP3A4_5, KCYP3A
Examples
1 2 | age <- 2
KCYP2C8(age)
|
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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