concentration_data_Linakis2020: Concentration data involved in Linakis 2020 vignette...
In httk: High-Throughput Toxicokinetics
concentration_data_Linakis2020 R Documentation
Concentration data involved in Linakis 2020 vignette analysis.
Description
These rat and human TK concentration vs. time (CvT) data are drawn from
the CvTdb (Sayre et el., 2020). Concentrations have all been converted to
the units of uM. All data are from inhalation studies.
Usage
concentration_data_Linakis2020
Format
A data.frame containing 2142 rows and 16 columns.
Details
Abbreviations used for sampling matrix:
BL : blood
EEB : end-exhaled breath
MEB : mixed exhaled breath
VBL : venous blood
ABL : arterial blood
EB : unspecified exhaled breath sample (assumed to be EEB)
PL: plasma
+W with work/exercise
Column Name Description
PREFERRED_NAME Substance preferred name
DTXSID Identifier for CompTox Chemical Dashboard
CASRN Chemical abstracts service registration number
AVERAGE_MASS Substance molecular weight g/mol
DOSE DOSE_U Inhalation exposure concentration in parts per million
EXP_LENGTH Duration of inhalation exposur
TIME Measurment time
TIME_U Time units for all times reported
CONC_SPECIES Species for study
SAMPLING_MATRIX Matrix analyzed
SOURCE_CVT Data source identifier within CvTdb
ORIG_CONC_U Original reported units for concentration
CONCENTRATION Analyte concentration in uM units
Author(s)
Matt Linakis
Source
Matt Linakis
References
\insertReflinakis2020developmenthttk
\insertRefsayre2020databasehttk
httk documentation built on Sept. 11, 2024, 9:32 p.m.
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| concentration_data_Linakis2020 | R Documentation |
Concentration data involved in Linakis 2020 vignette analysis.
Description
These rat and human TK concentration vs. time (CvT) data are drawn from the CvTdb (Sayre et el., 2020). Concentrations have all been converted to the units of uM. All data are from inhalation studies.
Usage
concentration_data_Linakis2020
Format
A data.frame containing 2142 rows and 16 columns.
Details
Abbreviations used for sampling matrix: BL : blood EEB : end-exhaled breath MEB : mixed exhaled breath VBL : venous blood ABL : arterial blood EB : unspecified exhaled breath sample (assumed to be EEB) PL: plasma +W with work/exercise
| Column Name | Description |
| PREFERRED_NAME | Substance preferred name |
| DTXSID | Identifier for CompTox Chemical Dashboard |
| CASRN | Chemical abstracts service registration number |
| AVERAGE_MASS | Substance molecular weight g/mol |
| DOSE DOSE_U | Inhalation exposure concentration in parts per million |
| EXP_LENGTH | Duration of inhalation exposur |
| TIME | Measurment time |
| TIME_U | Time units for all times reported |
| CONC_SPECIES | Species for study |
| SAMPLING_MATRIX | Matrix analyzed |
| SOURCE_CVT | Data source identifier within CvTdb |
| ORIG_CONC_U | Original reported units for concentration |
| CONCENTRATION | Analyte concentration in uM units |
Author(s)
Matt Linakis
Source
Matt Linakis
References
\insertReflinakis2020developmenthttk \insertRefsayre2020databasehttk
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