resmean.phreg: Restricted mean for stratified Kaplan-Meier or Cox model with...

In mets: Analysis of Multivariate Event Times

Restricted mean for stratified Kaplan-Meier or Cox model with martingale standard errors

Description

Restricted mean for stratified Kaplan-Meier or stratified Cox with martingale standard error. Standard error is computed using linear interpolation between standard errors at jump-times. Plots gives restricted mean at all times. Years lost can be computed based on this and decomposed into years lost for different causes using the cif.yearslost function that is based on integrating the cumulative incidence functions. One particular feature of these functions are that the restricted mean and years-lost are computed for all event times as functions and can be plotted/viewed. When times are given and beyond the last event time withn a strata the curves are extrapolated using the estimates of cumulative incidence.

Usage

resmean.phreg(x, times = NULL, covs = NULL, ...)

Arguments

x	phreg object
times	possible times for which to report restricted mean
covs	possible covariate for Cox model
...	Additional arguments to lower level funtions

Author(s)

Thomas Scheike

Examples

data(bmt); bmt$time <- bmt$time+runif(408)*0.001
out1 <- phreg(Surv(time,cause!=0)~strata(tcell,platelet),data=bmt)

rm1 <- resmean.phreg(out1,times=10*(1:6))
summary(rm1)
par(mfrow=c(1,2))
plot(rm1,se=1)
plot(rm1,years.lost=TRUE,se=1)

## years.lost decomposed into causes
drm1 <- cif.yearslost(Event(time,cause)~strata(tcell,platelet),data=bmt,times=10*(1:6))
summary(drm1)

mets documentation built on May 29, 2024, 3:51 a.m.