coverage: Coverage as expected number of peptides given all possible...

In peptider: Evaluation of Diversity in Nucleotide Libraries

Description

Coverage of library of size N given random sampling from the pool of all possible peptides according to probabilities determined according to the library scheme.

Usage

coverage(k, libscheme, N, lib = NULL, variance = FALSE)

Arguments

k	length of peptide sequences
libscheme	Name (character vector) or definition (data frame) of scheme
N	size of the library
lib	library scheme
variance	return the variance instead of the expected value

Value

coverage index between 0 and 1

Examples

coverage(2, "NNN", 10^3)
coverage(2, "NNK", 10^3)
coverage(2, "2020", 10^3) ## 20/20 coverage is not 1 because of random sampling.

Example output

[1] 0.7773061
[1] 0.8107846
[1] 0.917915

peptider documentation built on May 2, 2019, 2:43 a.m.