system_set_iiv: Set Variability Terms

In ubiquity: PKPD, PBPK, and Systems Pharmacology Modeling Tools

Set Variability Terms

Description

Set elements of the current variance covariance matrix specified in the system file with <IIV:?:?> ?, <IIVCOR:?:?>?, <IIVSET:?:?> ?, <IIVCORSET:?:?>?

Usage

system_set_iiv(cfg, IIV1, IIV2, value)

Arguments

cfg	ubiquity system object
IIV1	row name of the variance/covariance matrix
IIV2	column name of the variance/covariance matrix element
value	value to assign to the variance/covariance matrix element

Value

Ubiquity system object with IIV information set

See Also

system_fetch_iiv

Examples

# Creating a system file from the mab_pk example
fr = system_new(file_name        = "system.txt", 
                system_file      = "mab_pk", 
                overwrite        = TRUE, 
                output_directory = tempdir())

# Building the system 
cfg = build_system(system_file  = file.path(tempdir(), "system.txt"),
      output_directory          = file.path(tempdir(), "output"),
      temporary_directory       = tempdir())

# Clearing all inputs
cfg = system_zero_inputs(cfg)

# Setting the covariance element for CL and Vc to 0.03
cfg = system_set_iiv(cfg,
                     IIV1 = "ETACL",
                     IIV2 = "ETAVc",
                     value=0.03)

ubiquity documentation built on May 29, 2024, 12:02 p.m.