Krebslabrep/SingleMoleculeFootprinting: Analysis tools for Single Molecule Footprinting (SMF) data

SingleMoleculeFootprinting is an R package providing functions to analyze Single Molecule Footprinting (SMF) data. Following the workflow exemplified in this vignette, the user will be able to perform basic data analysis of SMF data with minimal coding effort. Starting from an aligned bam file, we show how to - perform quality controls over sequencing libraries, - extract methylation information at the single molecule level accounting for the two possible kind of SMF experiments (single enzyme or double enzyme) - classify single molecules based on their patterns of molecular occupancy - plot SMF information at a given genomic location

Getting started

Package details

Bioconductor views Coverage DNAMethylation DataRepresentation Epigenetics MethylSeq NucleosomePositioning QualityControl
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
Krebslabrep/SingleMoleculeFootprinting documentation built on April 11, 2021, 6:50 p.m.