signatureEnrichment: Performs sample stratification based on signature...

In PoisonAlien/maftools: Summarize, Analyze and Visualize MAF Files

Performs sample stratification based on signature contribution and enrichment analysis.

Description

Performs k-means clustering to assign signature to samples and performs enrichment analysis. Note - Do not use this function. This will be removed in future updates.

Usage

signatureEnrichment(maf, sig_res, minMut = 5, useCNV = FALSE, fn = NULL)

Arguments

maf	an MAF object used for signature analysis.
sig_res	Signature results from extractSignatures
minMut	Consider only genes with minimum this number of samples mutated. Default 5.
useCNV	whether to include copy number events. Only applicable when MAF is read along with copy number data. Default TRUE if available.
fn	basename for output file. Default NULL.

Value

result list containing p-values

See Also

plotEnrichmentResults

PoisonAlien/maftools documentation built on May 8, 2024, 8:30 a.m.