RNAhybridR: Find minimum free energy hybridisations of a long (target)...

Description Usage Arguments Examples

Description

This function is the R version of RNAhybrid by Rehmsmeier et al., RNA, 10:1507-1517, 2004. The hybridisation is performed in a kind of domain mode, ie. the short sequence is hybridised to the best fitting parts of the long one. The command line tool RNAhybrid needs to be installed (version 2.1 from http://bibiserv.techfak.uni-bielefeld.de/rnahybrid/dl_pre-page.html). There is no I/O activity so this function can be easily parallelized.

Usage

1
RNAhybridR(seq.target, seq.query, b = 1)

Arguments

seq.target

a character vector with the long nucleotide sequence

seq.query

a character vector with the short nucleotide sequence

b

maximal number of hits to show. Hits with increasing minimum free energy (reminder: larger energies are worse) are shown untill there are no more hits. Hits may only overlap at dangling bases (5' or 3' unpaired end of target).

Examples

1
a <- RNAhybridR("AACCTTGG", "ACTG")

Santaris/seqtools documentation built on May 9, 2019, 12:44 p.m.