View source: R/run_deconstructSigs.R
run_deconstructSigs | R Documentation |
This function gets called internally by trinuc_mutation_rates() for each tumor in a CESAnalysis, accepting a data.frame of mutation counts and returning a data.frame of signature weights.
run_deconstructSigs(
tumor_trinuc_counts,
signatures_df,
signatures_to_remove,
tri.counts.method
)
tumor_trinuc_counts |
one-row data.frame of trinuc variant counts (in deconstructSigs order) for one tumor |
signatures_df |
data.frame of signatures (see COSMIC v3 signatures included with package for format) |
signatures_to_remove |
names of signatures in signatures_df to keep out of deconstructSigs and assign zero weights |
tri.counts.method |
exome/genome trinucleotide content normalization argument to pass to deconstructSigs (see its docs) |
a data.frame of signature weights
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