methylKit is an R package for DNA methylation analysis and annotation from high-throughput bisulfite sequencing. The package is designed to deal with sequencing data from RRBS and its variants, but also target-capture methods and whole genome bisulfite sequencing. It also has functions to analyze base-pair resolution 5hmC data from experimental protocols such as oxBS-Seq and TAB-Seq. Methylation calling can be performed directly from Bismark aligned BAM files.
Package details |
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| Author | Altuna Akalin [aut, cre], Matthias Kormaksson [aut], Sheng Li [aut], Arsene Wabo [ctb], Adrian Bierling [aut], Alexander Blume [aut], Katarzyna Wreczycka [ctb] |
| Bioconductor views | DNAMethylation MethylSeq Sequencing |
| Maintainer | Altuna Akalin <aakalin@gmail.com>, Alexander Blume <alex.gos90@gmail.com> |
| License | Artistic-2.0 |
| Version | 1.33.3 |
| URL | https://github.com/al2na/methylKit |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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