scale_nUMI: Scale for nUMI (UMI Count) to generate CNV scores

In dkzhang777/SlideCNA: Calls Copy Number Alterations from Slide-Seq Data

Scale for nUMI (UMI Count) to generate CNV scores

Description

This function re-scales expression intensities to be in a smaller range, normalizes for nUMI per bin, and subtracts reference bead signal

Usage

scale_nUMI(dat_bin, thresh_hard = FALSE)

Arguments

dat_bin	data.table of relative expression intensities per bin
thresh_hard	TRUE if using strict thresholds for expression thresholds and FALSE if adjusting thresholds based on 1 + or - the mean of absolute min and max values

Value

data.table of CNV scores per bin

dkzhang777/SlideCNA documentation built on Jan. 25, 2025, 5:53 p.m.