scalefit: Subfunction for scale_nUMI that normalizes a given bin for...

In dkzhang777/SlideCNA: Calls Copy Number Alterations from Slide-Seq Data

Subfunction for scale_nUMI that normalizes a given bin for UMI count and centers the mean CNV score at 1

Description

This function re-scales expression intensities to be in a smaller range, normalizes for nUMI per bin, and centers the CNV scores to have a mean of 1

Usage

scalefit(obj, nbin, start, end)

Arguments

obj	data.table of relative expression intensities per bin
nbin	nUMIs in that specific bin
start	lower bound of CNV scores
end	upper bound of CNV scores

Value

vector of adjusted CNV scores for that bins with nbin number of nUMIs within the range (inclusive) of start to end

dkzhang777/SlideCNA documentation built on Jan. 25, 2025, 5:53 p.m.