Description Usage Arguments Author(s)
Generate a CN probability vector.
1 | getCNprob(readCount, p, r, segLen, binLen, maxCN = 5, alpha = 0.05)
|
readCount |
Total number of read counts (W+C) in all cells in this segment. |
p |
The p parameter of the NB distribution. |
r |
Dispersion parameter for the total number of read counts (W+C in all cells) in a bin with a diploid copy number (2). |
segLen |
The length of the segment. |
binLen |
The length of the bins used for estimating the NB parameters. |
maxCN |
The maximum number of CNs. |
alpha |
The coefficient of NB dispersion parameter for the number of background reads. |
Maryam Ghareghani
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