E.coli_iJR904: Ecoli genome-scale model

In hettling/BiGGR: Constraint based modeling in R using metabolic reconstruction databases

Description

An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR). The dataset was generated by downloading the SBML file of the reconstruction (http://bigg.ucsd.edu/bigg/exportSelect.pl) which was subsequently converted into an object of class SBML using the rsbml_read function from the rsbml package.

Usage

data(E.coli_iJR904)

Format

An sbml object of class rsbml

Details

Note that the files in the BiGG database fail the unit consistancy check of the rsbml_read function. To avoid unit checking when creating SBML objects, the substance units in the reaction tags were parsed out from the database SBML files (see example below).

Source

http://bigg.ucsd.edu/bigg/exportSelect.pl

References

Reed, J.L., Vo, T.D., Schilling, C.H., and Palsson, B.O., An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR), Genome Biology, 4(9): R54.1-R54.12 (2003).

Examples

## Not run: 
##The dataset was generated as follows:
##SBML_export.xml was downloaded from http://bigg.ucsd.edu/bigg/exportSelect.pl
##and a newline was added at the end of the file
file <- "SBML_export.xml"
string <- paste(readLines(file), collapse="\n")
##Parse out units to avoid validation error
string <- gsub("units=\".+?\"", "", string)
E.coli_iJR904 <- rsbml_read(text=string) 

## End(Not run)

##load data and get all reaction IDs
data(E.coli_iJR904)
model <- E.coli_iJR904@model
##get all reaction identifiers
sapply(model@reactions, id)

hettling/BiGGR documentation built on April 17, 2020, 5:19 a.m.