adjust_for_safety_rule: Adjust Dose-Response Table when Safety Rule Invoked
In jiyingz/clinicalMPI: The novel modified probability interval (mPI) phase I clinical trial design
View source: R/adjust_for_safety_rule.R
adjust_for_safety_rule R Documentation
Adjust Dose-Response Table when Safety Rule Invoked
Description
Adjust dose availabilities given that the safety rule was invoked, if dose sample size >= 6 (if sample size < 6, choose to stay and explore dose further, so no availabilities are changed).
The dose that invoked the safety rule and any higher doses will be made unavailable for future consideration.
Usage
dose_info = adjust_for_safety_rule(120, dose_info) #if dose level 120 invoked safety rule
Arguments
dose
A numeric dose level that violated the safety rule
dose_info
Dataframe containing
[dose level | availability | N_d | X_d | Y_d | Z_d | pf | pe | pt]
Value
Updated dose-response table dataframe with adjusted availabilities
jiyingz/clinicalMPI documentation built on Jan. 19, 2024, 5:58 a.m.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
View source: R/adjust_for_safety_rule.R
| adjust_for_safety_rule | R Documentation |
Adjust Dose-Response Table when Safety Rule Invoked
Description
Adjust dose availabilities given that the safety rule was invoked, if dose sample size >= 6 (if sample size < 6, choose to stay and explore dose further, so no availabilities are changed). The dose that invoked the safety rule and any higher doses will be made unavailable for future consideration.
Usage
dose_info = adjust_for_safety_rule(120, dose_info) #if dose level 120 invoked safety rule
Arguments
dose |
A numeric dose level that violated the safety rule |
dose_info |
Dataframe containing [dose level | availability | N_d | X_d | Y_d | Z_d | pf | pe | pt] |
Value
Updated dose-response table dataframe with adjusted availabilities
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
Embedding an R snippet on your website
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.