setup: Dose-Response Table Setup

In jiyingz/clinicalMPI: The novel modified probability interval (mPI) phase I clinical trial design

Dose-Response Table Setup

Description

Set up dose response-tracking table documenting the current dose's availability status, sample size, and futility, efficacy, and toxicity counts and corresponding probabilities. This table should be updated every time new cohort responses are available.

Usage

doses = c(60,80,100,120,140)
dose_info = setup(doses)

Arguments

doses

Vector of ordered dose levels

Value

An empty data frame in format

[dose level | availability | N_d | X_d | Y_d | Z_d | pf | pe | pt]:

• dose_lvl – dose level

• availability – whether dose is available for further testing

• N_d – sample size

• X_d – futility counts

• Y_d – efficacy counts

• Z_d – toxicity counts

• pf – estimated chance of futility

• pe – estimated chance of efficacy

• pt – estimated chance of toxicity

jiyingz/clinicalMPI documentation built on Jan. 19, 2024, 5:58 a.m.