check_safety_rule: Check Safety Rule
In jiyingz/clinicalMPI: The novel modified probability interval (mPI) phase I clinical trial design
View source: R/check_safety_rule.R
check_safety_rule R Documentation
Check Safety Rule
Description
Check if an available dose violates safety rule (toxicity count/sample size > safety threshold zeta).
Usage
check_safety_rule(80, dose_info, 0.8)
Arguments
dose
A numeric dose level (assumed to be available)
dose_info
Dataframe containing
[dose level | availability | N_d | X_d | Y_d | Z_d | pf | pe | pt]
zeta
Invoke stopping rule if more than this proportion of subjects exhibit toxicity
Value
Boolean T/F whether safety rule was violated
jiyingz/clinicalMPI documentation built on Jan. 19, 2024, 5:58 a.m.
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View source: R/check_safety_rule.R
| check_safety_rule | R Documentation |
Check Safety Rule
Description
Check if an available dose violates safety rule (toxicity count/sample size > safety threshold zeta).
Usage
check_safety_rule(80, dose_info, 0.8)
Arguments
dose |
A numeric dose level (assumed to be available) |
dose_info |
Dataframe containing [dose level | availability | N_d | X_d | Y_d | Z_d | pf | pe | pt] |
zeta |
Invoke stopping rule if more than this proportion of subjects exhibit toxicity |
Value
Boolean T/F whether safety rule was violated
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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