select_highestprob_interval: Select Model

In jiyingz/clinicalMPI: The novel modified probability interval (mPI) phase I clinical trial design

Select Model

Description

Select the probability region (model) with highest posterior probability, given current results. Note that for generalizability, this function currently calculates probabilities for regions completely falling within the pf+pt <=1 region.

Usage

selected = select_highestprob_interval(dose_info, pf_matrix, pt_matrix)
best_pf = selected$best_pf
best_pt = selected$best_pt

Arguments

dose_info	Dataframe containing [dose level | availability | N_d | X_d | Y_d | Z_d | pf | pe | pt]
pf_matrix	Matrix containing start and end points of futility (pf) intervals
pt_matrix	Matrix containing start and end points of toxicity (pt) intervals

Value

A list containing:

• post_probs – a matrix of posterior probailities per region (model)

• best_pf – futility interval index for chosen model

• best_pt – toxicity interval index for chosen model

jiyingz/clinicalMPI documentation built on Jan. 19, 2024, 5:58 a.m.