Repitope: Repitope: Epitope immunogenicity prediction via TCR-peptide...

RepitopeR Documentation

Repitope: Epitope immunogenicity prediction via TCR-peptide contact potential profiling

Description

In silico screening of immunogenic epitopes among the vast amount of MHC-loaded peptides is a critical step toward effective precision immunotherapy. Although various sequence-based prediction models have been proposed, none of them has ever achieved meaningful accuracy and robustness. Here, we developped a framework that enables accurate classification of immunogenic epitopes and non-immunogenic MHC ligands.


masato-ogishi/Repitope documentation built on Feb. 14, 2023, 5:47 a.m.