FilterFromCNVs: FilterFromCNVs

Description Usage Arguments Details Value Author(s) Source Examples

Description

FilterFromCNVs: Filter CNV from other methods.

Usage

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FilterFromCNVs(CNVs, PathRawData, MinNumSNPs = 10, Source = "iPsychCNV",
  Skip = 0, Cores = 1)

Arguments

CNVs:

Data frame with CNVs.

PathRawData:

The path to the raw data files containing Log R Ratio (LRR) and B Allele Frequency (BAF) values. Example: "/media/NeoScreen/NeSc_home/ILMN/iPSYCH/Version2".

MinNumSNPs:

Minimum number of SNPs per CNV, default = 10.

Source:

Which method is the original call, default = iPsychCNV.

Skip:

Integer, the number of rows of the data file that should be skipped before beginning tp read the data. Use if file has comments, default = 0.

Cores:

Number of cores to run in parallel, default = 1.

Details

Specifically designed to reduce false positive CNVs and handle noisy data from amplified DNA on phenylketonuria (PKU) cards. The function is a pipeline using many subfunctions.

Value

Data frame with the estimated copy number for each chromosome.

Author(s)

Marcelo Bertalan, Louise K. Hoeffding.

Source

http://biopsych.dk/iPsychCNV

Examples

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LongRoi <- MakeLongMockSample(Mean=c(-0.6, -0.3, 0.3, 0.6), Size=c(200, 400, 600))
# GADA
Sample <- read.table("LongMockSample.tab", sep="\t", header=TRUE, stringsAsFactors=F)
Gada <- RunGada(Sample)
Gada.filter <- FilterFromCNVs(CNVs=Gada, PathRawData=".", MinNumSNPs=10, Source="Gada", Skip=0, Cores=1)
See iPsychCNV tutorial for more examples
http://biopsych.dk/iPsychCNV/tutorial.html

mbertalan/iPsychCNV documentation built on May 22, 2019, 12:19 p.m.