reference_aware: English Adaptation of the WHO AWaRe Index

reference_awareR Documentation

English Adaptation of the WHO AWaRe Index

Description

This ‘AWaRe Index’ is a classification by the World Health Organisation of key antibiotics into three categories \insertCiteSharland2018Ramses to:

  • improve access (Access)

  • monitor important antibiotics (Watch) and

  • preserve effectiveness of ‘last resort’ antibiotics (Reserve).

It was adapted by Public Health England for antibiotic stewardship and quality improvement in English hospitals \insertCitePHE-aware2019Ramses.

The version included in Ramses contains an additional row for metronidazole J01XD01 administered orally (classified as Access). This is sometimes used in combination with other antibacterials that do not cover anaerobic organisms, but is not present in the Anatomical Therapeutic Chemical (ATC) classification.

Usage

reference_aware

Format

A data frame with 208 antimicrobial agents, referenced against the World Health Organisation's Anatomical Therapeutic Chemical (ATC) classification \insertCiteWHO-ATC2020Ramses, Public Health England's AWaRe Indices, and the SNOMED CT medical product concept codes and names. It contains 6 columns:

ATC_code

ATC code of the antibiotic

ATC_route

route of administration as defined in the ATC ("O" = oral; "P" = parenteral; "R" = rectal; "V" = vaginal)

ATC_name

ATC name of the antibiotic

aware_category

AWaRe index ("Access", "Watch", "Reserve")

version

AWaRe Index version (eg. "WHO", "England")

year

AWaRe Index version year

VTM_code

SNOMED CT medicinal product code/Virtual Therapeutic Moiety code in the SNOMED CT UK Drug Extension \insertCiteSNOMEDDrugUK2020Ramses

VTM_name

SNOMED CT medicinal product code/Virtual Therapeutic Moiety name in the SNOMED CT UK Drug Extension \insertCiteSNOMEDDrugUK2020Ramses

Source

Adapted from \insertCiteWHO-aware2019,PHE-aware2019;textualRamses with Virtual Therapeutic Moiety equivalents from the NHS Dictionary of Medicines (dm+d) \insertCiteSNOMEDDrugUK2020Ramses.

References

\insertAllCited

Examples

data("reference_aware")
head(reference_aware)

ramses-antibiotics/ramses-package documentation built on Feb. 13, 2024, 1:01 p.m.