lik_calc_fittedSD: Find the likelihood of data given proposed parameters

In shackett/simmer: Systematic Identification of Meaningful Metabolic Enzyme Regulation

Description

Determine the likelihood of predicted flux as a function of metabolite abundance and kinetics parameters relative to actual flux

Usage

lik_calc_fittedSD(proposed_params, kineticPars, all_species, rxnEquations,
  omic_data, kinetically_differing_isoenzymes)

Arguments

proposed_params	non-linear kinetic parameters to be testing using the reaction equation
kineticPars	table summarizing which species all non-linear kinetic parameters correspond to
all_species	all_species table summarizing the types of all reaction species
rxnEquations	expressions for reaction equations
omic_data	abundances and uncertainties of reaction species and flux: setup in format_omic_data
kinetically_differing_isoenzymes	True-False: does only one equation exist for the reaction (false) or are are reaction equations isoenzyme specific (true)

Value

a numeric log-likelihood

shackett/simmer documentation built on May 29, 2019, 8:06 p.m.