CalculateCSS: Calculate Combination Sensitivity Score
In shuyuzheng/synergyfinder: Calculate and Visualize Synergy Scores for Drug Combinations
View source: R/calculate_sensitivity_score.R
CalculateCSS R Documentation
Calculate Combination Sensitivity Score
Description
This function will calculate the Combination Sensitivity Score (CSS) for a
drug combination block.
Usage
CalculateCSS(response, ic50)
Arguments
response
A data frame. It must contain the columns: "conc1", "conc2",
..., for the concentration of the combined drugs and "response" for the
observed %inhibition at certain combination.
ic50
A list. It contains the relative IC50 for all the drugs in the
combination.
Value
A data frame. It contains the CSS for each drug will one of the other
drugs is at its IC50 and summarized CSS for the whole block.
Author(s)
Shuyu Zheng shuyu.zheng@helsinki.fi
Jing Tang jing.tang@helsinki.fi
shuyuzheng/synergyfinder documentation built on Feb. 20, 2023, 11:33 p.m.
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View source: R/calculate_sensitivity_score.R
| CalculateCSS | R Documentation |
Calculate Combination Sensitivity Score
Description
This function will calculate the Combination Sensitivity Score (CSS) for a drug combination block.
Usage
CalculateCSS(response, ic50)
Arguments
response |
A data frame. It must contain the columns: "conc1", "conc2", ..., for the concentration of the combined drugs and "response" for the observed %inhibition at certain combination. |
ic50 |
A list. It contains the relative IC50 for all the drugs in the combination. |
Value
A data frame. It contains the CSS for each drug will one of the other drugs is at its IC50 and summarized CSS for the whole block.
Author(s)
Shuyu Zheng shuyu.zheng@helsinki.fi
Jing Tang jing.tang@helsinki.fi
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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