.SolveLoewe | R Documentation |
Solve the Loewe Additive Effect for Concentration Combinations Isobologram
.SolveLoewe(concs, drug_par, drug_type, nsteps = 100)
concs |
A numeric vector. It contains the concentrations of tested drugs. |
drug_par |
A numeric vector. The parameters in fitted dose response curve. |
drug_type |
The type of model used to fit dose response curve. |
nsteps |
The total steps to calculate concentration combinations approaching to the true Loewe effect. |
A list contains 3 items:
y_loewe the predicted Loewe additive effect which closes to .
x_select the expected concentrations for each drug to achieve y_loewe.
distance the smallest distance
Shuyu Zheng shuyu.zheng@helsinki.fi
Jing Tang jing.tang@helsinki.fi
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