dot-SolveLoewe: Solve the Loewe Additive Effect for Concentration...

.SolveLoeweR Documentation

Solve the Loewe Additive Effect for Concentration Combinations Isobologram

Description

Solve the Loewe Additive Effect for Concentration Combinations Isobologram

Usage

.SolveLoewe(concs, drug_par, drug_type, nsteps = 100)

Arguments

concs

A numeric vector. It contains the concentrations of tested drugs.

drug_par

A numeric vector. The parameters in fitted dose response curve.

drug_type

The type of model used to fit dose response curve.

nsteps

The total steps to calculate concentration combinations approaching to the true Loewe effect.

Value

A list contains 3 items:

  • y_loewe the predicted Loewe additive effect which closes to .

  • x_select the expected concentrations for each drug to achieve y_loewe.

  • distance the smallest distance

Author(s)


shuyuzheng/synergyfinder documentation built on Feb. 20, 2023, 11:33 p.m.