calculateCellLineMean: Calculate cell line mean

In cTRAP: Identification of candidate causal perturbations from differential gene expression data

Description

Calculate cell line mean

Usage

calculateCellLineMean(data, cellLine, metadata, rankPerCellLine)

Arguments

data	Data table: comparison against CMap data
cellLine	Character: perturbation identifiers as names and respective cell lines as values
metadata	Data table: data metadata
rankPerCellLine	Boolean: rank results based on both individual cell lines and mean scores across cell lines (TRUE) or based on mean scores alone (FALSE)? If cellLineMean = FALSE, individual cell line conditions are always ranked.

Value

A list with two items:

data

input data with extra rows containing cell line average scores (if calculated)

rankingInfo

data table with ranking information

metadata

metadata associated with output data, including for identifiers regarding mean cell line scores

cTRAP documentation built on Nov. 8, 2020, 10:58 p.m.