scmod1.robust: Subtype Clustering Model using ESR1, ERBB2 and AURKA modules...

Description Usage Format Source References Examples

Description

List of parameters defining the Subtype Clustering Model as published in Desmedt et al 2008.

Usage

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Format

List of parameters for SCMOD1:

parameters

List of parameters for the mixture of three Gaussians (ER-/HER2-, HER2+ and ER+/HER2-) that define the Subtype Clustering Model. The structure is the same than for an Mclust object.

cutoff.AURKA

Cutoff for AURKA module score in order to identify ER+/HER2- High Proliferation (aka Luminal B) tumors and ER+/HER2- Low Proliferation (aka Luminal A) tumors.

mod

ESR1, ERBB2 and AURKA modules.

Source

http://clincancerres.aacrjournals.org/content/14/16/5158.abstract?ck=nck

References

Desmedt C, Haibe-Kains B, Wirapati P, Buyse M, Larsimont D, Bontempi G, Delorenzi M, Piccart M, and Sotiriou C (2008) "Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes", Clinical Cancer Research, 14(16):5158–5165.

Examples

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genefu documentation built on Nov. 1, 2018, 2:25 a.m.