Gene expression, annotations and clinical data from van de Vijver et al. 2002

Description

This dataset contains (part of) the gene expression, annotations and clinical data as published in van de Vijver et al. 2002.

Usage

1

Format

nkis is a dataset containing three matrices:

data.nkis

Matrix containing gene expressions as measured by Agilent technology (dual-channel, oligonucleotides

annot.nkis

Matrix containing annotations of Agilent microarray platform

demo.nkis

Clinical information of the breast cancer patients whose tumors were hybridized

Details

This dataset represent only partially the one published by van de Vijver et al. in 2008. Indeed, only part of the patients (150) and gene expressions (922) are contained in data.nkis.

Source

http://www.nature.com/nature/journal/v415/n6871/full/415530a.html

References

M. J. van de Vijver and Y. D. He and L. van't Veer and H. Dai and A. M. Hart and D. W. Voskuil and G. J. Schreiber and J. L. Peterse and C. Roberts and M. J. Marton and M. Parrish and D. Atsma and A. Witteveen and A. Glas and L. Delahaye and T. van der Velde and H. Bartelink and S. Rodenhuis and E. T. Rutgers and S. H. Friend and R. Bernards (2002) "A Gene Expression Signature as a Predictor of Survival in Breast Cancer", New England Journal of Medicine, 347(25):1999–2009

Examples

1

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