plotHeatmap: A function to generate heatmap panels sorted by integrated...

Description Usage Arguments Details Value Author(s) References See Also Examples

View source: R/plotHeatmap.R

Description

A function to generate heatmap panels sorted by integrated cluster assignment.

Usage

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plotHeatmap(fit,datasets,type=c("gaussian","binomial","poisson","multinomial"),
	sample.order=NULL,row.order=NULL,sparse=NULL,threshold=rep(0.25,length(datasets)),
	width=5,scale=rep("none",length(datasets)),col.scheme=rep(list(bluered(256)),
	length(datasets)), chr=NULL, plot.chr=NULL, cap=NULL)

Arguments

fit

A iCluster object.

datasets

A list object of data matrices.

type

Types of data in the datasets.

sample.order

User supplied cluster assignment.

row.order

A vector of logical values each specificy whether the genomic features in the corresponding data matrix should be reordered by similarity. Default is TRUE.

sparse

A vector of logical values each specificy whether to plot the top cluster-discriminant features. Default is FALSE.

threshold

When sparse is TRUE, a vector of threshold values to include the genomic features for which the absolute value of the associated coefficient estimates fall in the top quantile. threshold=c(0.25,0.25) takes the top quartile most discriminant features in data type 1 and data type 2 for plot.

width

Width of the figure in inches

scale

A vector of logical values each specify whether data should be scaled. Default is FALSE.

col.scheme

Color scheme. Can use bluered(n) in gplots R package.

chr

A vector of chromosome number.

plot.chr

A vector of logical values each specificy whether to annotate chromosome number on the left of the panel. Typically used for copy number data type. Default is FALSE.

cap

Image color option

Details

The samples are ordered by the cluster assignment using the R code: order(fit$clusters). For each data set, the features are ordered by hierarchical clustering of the features using the complete method and 1-correlation coeffient as the distance.

Value

no value returned.

Author(s)

Ronglai Shen shenr@mskcc.org

References

Ronglai Shen, Adam Olshen, Marc Ladanyi. (2009). Integrative clustering of multiple genomic data types using a joint latent variable model with application to breast and lung cancer subtype analysis. Bioinformatics 25, 2906-2912.

Ronglai Shen, Qianxing Mo, Nikolaus Schultz, Venkatraman E. Seshan, Adam B. Olshen, Jason Huse, Marc Ladanyi, Chris Sander. (2012). Integrative Subtype Discovery in Glioblastoma Using iCluster. PLoS ONE 7, e35236

See Also

iCluster,iCluster2

Examples

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# see iManual.pdf

Example output

Loading required package: parallel

iClusterPlus documentation built on Nov. 8, 2020, 8:01 p.m.