This function implements a reverse version of the interquantile filtering proposed by Heydebreck in 2004 to select low variance genelevel probe set. To be used to remove putative differentially expressed genes that will make more difficult the detection of alternative splicing events.
This function can be used in a analysis focused to the detection of alternative splicing events. The aim of this non specific filtering is to remove the genes that are likely to carry information about the phenotypes under investigation at gene level. This filtering remove genes that show strong changes within the experimental points at the gene level.
Raffaele A Calogero
Heydebreck et al. Bioconducotor project Papers 2004
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