kersplatEstBCV: Estimate Kersplat BCV parameters
In splatter: Simple Simulation of Single-cell RNA Sequencing Data

Description Usage Arguments Details Value

Estimate Biological Coefficient of Variation (BCV) parameters for the Kersplat simulation

1	kersplatEstBCV(counts, params, verbose)

`counts`	counts matrix.
`params`	KersplatParams object to store estimated values in.
`verbose`	logical. Whether to print progress messages

The estimateDisp function is used to estimate the common dispersion across the dataset. An exponential correction is applied based on fitting an exponential relationship between simulated and estimated values. If this results in a negative dispersion a simpler linear correction is applied instead.

KersplatParams object with estimated BCV parameters

splatter documentation built on Dec. 3, 2020, 2:01 a.m.