kersplatSimAmbientCounts: Simulate Kersplat ambient counts

Description Usage Arguments Details Value

View source: R/kersplat-simulate.R

Description

Simulate Kersplat ambient counts

Usage

1
kersplatSimAmbientCounts(sim, params, verbose)

Arguments

sim

SingleCellExperiment containing simulation.

params

KersplatParams object with simulation parameters.

verbose

logical. Whether to print progress messages

Details

The overall expression profile to calculated by averaging the cell counts of the (non-empty) cells. This is then multiplied by the ambient library sizes to get a mean for each cell. Counts are then sampled from a Poisson distribution using these means.

Value

SingleCellExperiment with ambient counts


splatter documentation built on Dec. 3, 2020, 2:01 a.m.