agep: Age Prediction from methylomic expression data

In wateRmelon: Illumina 450 methylation array normalization and metrics

Description

Predict age of samples using Horvaths Coefficients

Usage

agep(betas, coeff=NULL, method=c('horvath','hannum') ,...)

Arguments

betas	Matrix of betas or MethyLumiSet or MethylSet object.
coeff	If NULL, will default to Horvaths coefficients. Otherwise can be supplied with vector of own coefficients with an intercept as first element.
method	currently either "horvath" or "hannum". If using "hannum" remember to call data(hannumCoef) before analysis and supply coeff with the hannum coefficients, otherwise will default to "horvath".
...	To pass to arguments to downstream functions to specify adult.age

Value

Returns matrix of predicted ages per sample.

Author(s)

Original Functions: Steve Horvath

wateRmelon Implementation: Leo Schalkwyk, Louis El Khoury

References

Horvath S: DNA methylation age of human tissues and cell types. Genome Biology 2013, 14:R115

Examples

data(melon)
data(coef)
agep(melon,coeff=coef)
# or
agep(betas(melon),coeff=coef)

wateRmelon documentation built on Nov. 8, 2020, 7:47 p.m.