norm_internal_subset: Internal subset normalization function

In OlinkAnalyze: Facilitate Analysis of Proteomic Data from Olink

Internal subset normalization function

Description

This function performs subset normalization using a subset of the samples from either or both reference and non-reference datasets. When all samples from each dataset are used, the function performs intensity normalization.

Usage

norm_internal_subset(
  ref_df,
  ref_samples,
  ref_name,
  ref_cols,
  not_ref_df,
  not_ref_samples,
  not_ref_name,
  not_ref_cols
)

Arguments

ref_df	The reference dataset to be used in normalization (required).
ref_samples	Character vector of sample identifiers to be used for adjustment factor calculation in the reference dataset (required).
ref_name	Project name of the reference dataset (required).
ref_cols	Named list of column names in the reference dataset (required).
not_ref_df	The non-reference dataset to be used in normalization (required).
not_ref_samples	Character vector of sample identifiers to be used for adjustment factor calculation in the non-reference dataset (required).
not_ref_name	Project name of the non-reference dataset (required).
not_ref_cols	Named list of column names in the non-reference dataset (required).

Value

Tibble or ArrowObject with the normalized dataset.

Author(s)

Klev Diamanti

OlinkAnalyze documentation built on Sept. 25, 2024, 9:07 a.m.