scoreThr: Determine numerically a threshold for the ranking score

In fcros: A Method to Search for Differentially Expressed Genes and to Detect Recurrent Chromosomal Copy Number Aberrations

Description

Given a log 10 transformed of the sorted ranking score values (dscore), this function determines numerically a threshold (inflection point) for significance of sequencing value level. User should specify the lower and the upper bounds of the slope region containing the inflection point.

Usage

scoreThr(dscore, deb, fin)

Arguments

dscore	transformed score values obtained using the function rankReads()
deb	integer for lower bound of the slope region containing the inflection point. User should perfom a plot to determine this value
fin	integer for upper bound of the slope region containing the inflection point. User should perfom a plot to determine this value

Value

This function returns two values: “pos” and “thr” which are the index or the number of genes with significant values and the score (-log10(score)) threshold

Author(s)

Doulaye Dembele [e-mail]

References

Dembele D, manuscript under preparation

Examples

#    data(fdata);

Example output

fcros documentation built on May 31, 2019, 5:03 p.m.