voomReads: Transformation of read count values

In fcros: A Method to Search for Differentially Expressed Genes and to Detect Recurrent Chromosomal Copy Number Aberrations

Description

This function allows to transform the count values associated with Sequencing reads. The purpose of this transformation is to allow applying normal-based microarray-like statistical methods to RNA-seq read counts. Log2 values are returned.

Usage

voomReads(x, Rm=1e+06)

Arguments

x	This is a read counts matrix
Rm	A constant used in the transformation

Value

This function returns a data matrix of the same size as input matrix x. The values of this matrix are expressed in log2 scale.

Author(s)

Doulaye Dembele [e-mail]

References

Charity W Law, Yunshun Chen, Wei Shi and Gordon K Smyth, voom: precision weights unlock linear model analysis tools for RNA-seq read counts,Genome Biology, 2014, 15R29

Examples

#   data(fdata);

Example output

fcros documentation built on May 31, 2019, 5:03 p.m.