impute: Impute of Low Density SNP Marker to High Density (Paternal...

View source: R/impute.R

imputeR Documentation

Impute of Low Density SNP Marker to High Density (Paternal Strand)

Description

Impute the paternal strand from low density to high density utilising high density sire haplotype.

Usage

impute(halfsib_genotype_ld, sire_hd, bmh_forwardVectorSize = 30, 
bmh_excludeFP = TRUE, bmh_nsap = 3)

Arguments

halfsib_genotype_ld

matrix half-sib genotypes with low density marker (one half-sib per row, with SNP ordered by mapping position in the columns. Data should be numeric. Use 0, 1 and 2 respectively for AA, AB and BB. Use 9 for missing data)

sire_hd

matrix haplotype of sire (this parameter can be sequence data or any phased sire - the matrix should have rownames which are the sample IDs and colnames which are the SNP names)

bmh_forwardVectorSize

integer number of heterozygous sites used to validate recombination events or check for genotyping errors

bmh_excludeFP

logical exclude SNPs that may cause heterozygous sites in the sire due to genotyping errors or map errors

bmh_nsap

integer number of SNPs per block

Value

Return an imputed half-sib matrix.

See Also

bmh, ssp and phf


hsphase documentation built on May 29, 2024, 2:20 a.m.