idem: Inference in Randomized Controlled Trials with Death and Missingness

Share:

In randomized studies involving severely ill patients, functional outcomes are often unobserved due to missed clinic visits, premature withdrawal or death. It is well known that if these unobserved functional outcomes are not handled properly, biased treatment comparisons can be produced. In this package, we implement a procedure for comparing treatments that is based on the composite endpoint of both the functional outcome and survival. The procedure considers missing data imputation with a sensitivity analysis strategy to handle the unobserved functional outcomes not due to death.

Author
Chenguang Wang [aut, cre], Andrew Leroux [aut, cre], Elizabeth Colantuoni [aut], Daniel O Scharfstein [aut]
Date of publication
2016-07-06 00:46:23
Maintainer
Chenguang Wang <cwang68@jhmi.edu>
License
GPL (>= 3)
Version
1.0

View on CRAN

Man pages

abc
Example dataset
chkPara
Check parameter specification
fit.model
Model fitting
get.bs.all
Boostrap analysis
get.imp.all
Impute missing data
get.mis.table
Generate table of missingness pattern frequencies
get.overall.rst
Hypothesis testing
get.theta.quantiles
Treatment effect estimation
idem-package
Inference in Randomized Clinical Trials with Death and...
idem-parameters
List of parameters for 'idem' analysis
plotCompleters
Plot data of completer
plotComposite
Cumulative Plot
plotContour
Contour plot of the sensitivity analysis results
plotImputed
Plot density of imputed values
plotMisPattern
Plot missing patterns
plotSurv
Plot survival curves
run.idem
Run Web-Based 'idem' application

Files in this package

idem
idem/inst
idem/inst/shiny
idem/inst/shiny/ui.R
idem/inst/shiny/server.R
idem/inst/shiny/www
idem/inst/shiny/www/tools.js
idem/inst/shiny/www/info.png
idem/inst/shiny/www/example.txt
idem/inst/shiny/www/composite_about.html
idem/inst/shiny/www/warning.png
idem/inst/shiny/www/help.png
idem/inst/shiny/www/texturebg2.jpg
idem/inst/shiny/www/error.png
idem/inst/shiny/www/success.png
idem/inst/shiny/www/texturebg.png
idem/inst/shiny/www/composite_upload.html
idem/inst/shiny/www/styles.css
idem/inst/shiny/composite_ui.R
idem/inst/shiny/report
idem/inst/shiny/report/report.pdf
idem/inst/shiny/report/report.Rmd
idem/inst/doc
idem/inst/doc/vignette.Rmd
idem/inst/doc/vignette.R
idem/inst/doc/vignette.html
idem/src
idem/src/Makevars
idem/src/idem.c
idem/NAMESPACE
idem/data
idem/data/abc.rda
idem/R
idem/R/idem_analysis.R
idem/R/idem_package.R
idem/R/idem_visualize.R
idem/R/idem_shiny.R
idem/R/idem_tools.R
idem/R/idem_imputation.R
idem/vignettes
idem/vignettes/vignette.Rmd
idem/MD5
idem/build
idem/build/vignette.rds
idem/DESCRIPTION
idem/man
idem/man/run.idem.Rd
idem/man/plotContour.Rd
idem/man/idem-parameters.Rd
idem/man/plotMisPattern.Rd
idem/man/get.bs.all.Rd
idem/man/abc.Rd
idem/man/plotImputed.Rd
idem/man/plotComposite.Rd
idem/man/chkPara.Rd
idem/man/idem-package.Rd
idem/man/get.overall.rst.Rd
idem/man/fit.model.Rd
idem/man/plotCompleters.Rd
idem/man/get.imp.all.Rd
idem/man/plotSurv.Rd
idem/man/get.theta.quantiles.Rd
idem/man/get.mis.table.Rd