idem: Inference in Randomized Controlled Trials with Death and Missingness

In randomized studies involving severely ill patients, functional outcomes are often unobserved due to missed clinic visits, premature withdrawal or death. It is well known that if these unobserved functional outcomes are not handled properly, biased treatment comparisons can be produced. In this package, we implement a procedure for comparing treatments that is based on the composite endpoint of both the functional outcome and survival. The procedure was proposed in Wang et al. (2016) <doi:10.1111/biom.12594>. It considers missing data imputation with a sensitivity analysis strategy to handle the unobserved functional outcomes not due to death.

Install the latest version of this package by entering the following in R:
install.packages("idem")
AuthorChenguang Wang [aut, cre], Andrew Leroux [aut, cre], Elizabeth Colantuoni [aut], Daniel O Scharfstein [aut], Trustees of Columbia University [cph] (tools/make_cpp.R, R/stanmodels.R)
Date of publication2017-04-23 15:18:32 UTC
MaintainerChenguang Wang <cwang68@jhmi.edu>
LicenseGPL (>= 3)
Version2.0

View on CRAN

Files

inst
inst/shiny
inst/shiny/ui.R inst/shiny/server.R
inst/shiny/www
inst/shiny/www/tools.js
inst/shiny/www/info.png
inst/shiny/www/example.txt
inst/shiny/www/composite_about.html
inst/shiny/www/warning.png
inst/shiny/www/help.png
inst/shiny/www/texturebg2.jpg
inst/shiny/www/error.png
inst/shiny/www/success.png
inst/shiny/www/texturebg.png
inst/shiny/www/composite_upload.html
inst/shiny/www/styles.css
inst/shiny/composite_ui.R
inst/shiny/report
inst/shiny/report/report.pdf
inst/shiny/report/report.Rmd
inst/doc
inst/doc/vignette.Rmd
inst/doc/vignette.R
inst/doc/vignette.html
exec
exec/idem.stan
src
src/Makevars
src/idem_init.c
src/idem.c
src/Modules.cpp
src/include
src/include/models.hpp
NAMESPACE
data
data/abc.rda
R
R/idem_analysis.R R/idem_package.R R/stanmodels.R R/idem_visualize.R R/idem_shiny.R R/idem_tools.R R/idem_imputation.R R/zzz.R
vignettes
vignettes/vignette.Rmd
MD5
build
build/vignette.rds
DESCRIPTION
man
man/imPlotSurv.Rd man/imPlotImputed.Rd man/idem-parameters.Rd man/imImpAll.Rd man/imChkPars.Rd man/abc.Rd man/imEstimate.Rd man/imImpSingle.Rd man/imPlotContour.Rd man/idem-package.Rd man/imFitModel.Rd man/imBs.Rd man/imPlotCompleters.Rd man/imPlotComposite.Rd man/imPlotMisPattern.Rd man/imMisTable.Rd man/imTest.Rd man/imShiny.Rd man/imNeedImp.Rd
cleanup
tools
tools/make_cpp.R
cleanup.win

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