antibiotox | R Documentation |

Seven antibiotics are: Neomycin sulfate(NEO), streptomycin sulfate(STR),
kanamycin sulfate(KAN), spectinomycin dihydrochloridehydrate(SPE), paromomycin
sulfate(PAR), dihydrostreptomycin sesquisulfate hydrate(DIH), and gentamycin
sulfate(GEN). Their toxicity on photobacteria Q67 were tested using
microplate toxicity analysis.

The concentration-responses include the toxicity of seven antibiotics,
two eecr mixtures, and ten mixtures designed by udcr. The curve fitting
information of seven antibiotics and a total of 12 mixtures.

data(antibiotox)

A list with concentration-response data of 7 antibiotics, 12 mixtures, and associated fitting information.

`PAR$x`

a numeric vector of concentrations

`PAR$y`

a numeric matrix of responses

`PAR$name`

name of test substance

`PAR$concNum`

the number of concentrations

`PAR$tierNum`

the number of repetitions

`PAR$type`

type of test substance

`sgl$model`

models used to fit the concentration-response data

`sgl$param`

fitted coefficients of concentration-response curves

`udcr.mix$model`

models used to fit the concentration-response data of udcr mixtures on photobacteria

`udcr.mix$param`

fitted coefficients of concentration-response curves

`udcr.pct`

the percentage of individual chemicals in the udcr mixtures

`eecr.mix$model`

models used to fit the concentration-response data of eecr mixtures on photobacteria

`eecr.mix$param`

fitted coefficients of concentration-response curves

`eecr.pct`

the proportion of individual chemicals in the eecr mixtures

Quantal responses[0, 1] are needed for curve fitting using the following six equaitons: i.e., Weibull, Logit, Hill, BCL, GL, BCW. The following equation could transform continous responses to quantal ones:

*E = \frac{{{I_0} - {I_i}}}{{{I_0}}}*

where *I_0* is the average of controls for inhibition tests or the average
of the maximum effect for stimulation tests and *I_i* the average
effect of the *i^{th}* treatment.

# example 1 ## Retrive the toxicity information of PAR on photobacteria. antibiotox$PAR # example 2 ## Retrive the toxicity information of two eecr mixtures on photobacteria. antibiotox$eecr.mix

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