AnalCorrHuman: AnalCorrHuman

In CaronLab/MHCIatlas: Package to reproduce data analysis and further explore the data depicted by Kubiniok et al. 2021 in 'Global Analysis of the Mammalian MHC class I Immunopeptidome at the Organism-Wide Scale'.

Description

Function to extract proteins which significanlty correlate with MHCI peptide counts across tissues and donors.

Usage

AnalCorrHuman(
  DfList_Human_ProteinCorrelations,
  pValue_Threshold = 0.05,
  rsq_Threshold = 0.4
)

Arguments

DfList_Human_ProteinCorrelations	Output from 'MakeCorrHuman' with parameter 'runAnalCorrHuman=FALSE'
pValue_Threshold	Protein correlations with a pValue smaller than this threshold are considered significant, Default: 0.05
rsq_Threshold	Min RSQ value at which protein is considered significantly correlation, both pValue and RSQ values have to be better or equal than threshold values, Default: 0.4

Details

This function should always be used as part of the function 'MakeCorrHuman', only to be run seperately to save on computation time/space

Value

Data frame with all human proteins subjected to correlations and annotated significance across donors

See Also

ggplot,aes,geom_path,scale_colour_brewer,geom_abline,theme,margin,labs,facet_grid,lims

Examples

## Not run: 
 df_corrhuman <- AnalCorrHuman(MakeCorrHumanRaw,pValue_Threshold = 0.05)

## End(Not run)

CaronLab/MHCIatlas documentation built on March 10, 2021, 12:38 a.m.